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| Product | Description | |
|---|---|---|
| Tenovin-6 | Tenovin-6, also known as Tnv-6, is a bioactive small molecule SIRT2 inhibitor with anti-neoplastic activity. Inhibition of the Sirtuin class of protein deacetylases with activation of p53 function is associated with the pro-apoptotic effects of Tnv-6 in many tumors. Synonyms: Tenovin-6; Tenovin 6; Tenovin6. CAS No. 1011557-82-6. Molecular formula: C25H34N4O2S. Mole weight: 454.63. |  |
| Tenovin-6 | Tenovin-6, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC 50 s of 21 μM, 10 μM, and 67 μM, respectively. Tenovin-6 also inhibits dihydroorotate dehydrogenase (DHODH) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1011557-82-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15510. |  |
| Tenovin-6 Hydrochloride | Tenovin-6 Hydrochloride, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 Hydrochloride inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC 50 s of 21 μM, 10 μM, and 67 μM, respectively. Tenovin-6 Hydrochloride also inhibits dihydroorotate dehydrogenase (DHODH) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1011301-29-3. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15510B. | |
| Tenovin 6 Hydrochloride | Tenovin-6 is the water soluble analog of Tenovin-1 (HY-13423) and acts as a potent SIRT1 (IC50=21 μM) and SIRT2 (IC50=10 μM) inhibitor as well as p53 activator. Synonyms: Tenovin 6 Hydrochloride; Tenovin6 Hydrochloride; Tenovin-6 Hydrochloride. Grades: >98%. CAS No. 1011301-29-3. Molecular formula: C25H35ClN4O2S. Mole weight: 491.09. | |
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