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TEPP-46 TEPP-46, an effective sensitizer of recombinant pyruvate kinase M2, has been found to decrease the formation of tumor in a mouse xenograft model. IC50: 92 nM (AC50). Uses: Tepp-46 has been found to decrease the formation of tumor in a mouse xenograft model. Synonyms: ML265; ML-265; ML 265; CID44246499; CID-44246499; CID 44246499; NCGC00186528; NCGC 00186528; NCGC-00186528; TEPP46; TEPP 46; TEPP-46; 6-[(3-aminophenyl)methyl]-4,6-dihydro-4-methyl-2-(methylsulfinyl)-5h-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one; ML265; TEPP 46; MLS006010294. Grades: 95%. CAS No. 1221186-53-3. Molecular formula: C17H16N4O2S2. Mole weight: 372.46. BOC Sciences 9
TEPP-46 TEPP-46 (ML-265) is a potent and selective pyruvate kinase M2 (PKM2) activator with an AC 50 of 92 nM, showing little or no effect on PKM1, PKL and PKR [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ML-265. CAS No. 1221186-53-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18657. MedChemExpress MCE

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