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NS8593 ((R)-N-(Benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine) An aminobenzimidazole derivative that selectively and reversibly blocks small conductance Ca2+-activated K+ channels (SK1-3; =420nM, 600nM, and 730nM for SK1, SK2, SK3, respectively) in a Ca2+-dependent manner. It mediates channel gating by interacting with gating structures deep within the inner pore vestibule where Ser507 and Ala532 are deemed to be important for inhibition. Interacts at a site that is distinct from the apamin binding site in SK channels. Can access high-affinity binding sites from both the inside and outside of the cell membrane. Does not affect QT intervals, but prolongs the atrial effective refractive period and prevents acetylcholine-induced atrial fibrillations in ex vivo and in vivo models. Also shown to reversibly block TRPM7 channel (IC50=1.6mM) in smooth muscle cells, primary podocytes, HEK293 cells expressing TRPM7, and ventricular myocytes in a Mg2+-dependent manner and blocks the motility of cells in culture. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
4-Methylbenzenesulfonate;n-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-1-ium-2-amine Heterocyclic Organic Compound. Alternative Names: CID59288, LS-95833, 2-(5,6,7,8-Tetrahydro-1-naphthylamino)-2-imidazoline p-toluenesulfonate, 2-Imidazoline, 2-(5,6,7,8-tetrahydro-1-naphthylamino)-, p-toluenesulfonate, 5,6,7,8-Tetrahydro-N-(2-imidazolin-2-yl)-1-naphthylamine p-toluenesulfonate, 1-NAPHTHYLAMINE, 5,6,7,8-TETRAHYDRO-N-(2-IMIDAZOLIN-2-YL)-, p-TOLUENESULFONATE, 102280-49-9. CAS No. 102280-49-9. Molecular formula: C20H25N3O3S. Mole weight: 387.496 g/mol. Purity: 0.96. IUPACName: 4-methylbenzenesulfonate; N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-1-ium-2-amine. Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)O. C1CCC2=C(C1)C=CC=C2NC3=NCCN3. Catalog: ACM102280499. Alfa Chemistry. 3
5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine Synonyms: 5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine; 5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthylamine. Grades: 95%. CAS No. 92050-16-3. Molecular formula: C14H21N. Mole weight: 203.32. BOC Sciences 5
N-(2,3-Dimethyl-5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1,3-oxazol-2-amine Heterocyclic Organic Compound. Alternative Names: CID59289, LS-95821, 1-Naphthylamine, 2,3-dimethyl-N-(2-oxazolinyl)-5,6,7,8-tetrahydro-, 2-(2,3-Dimethyl-5,6,7,8-tetrahydro-1-naphthylamino)-2-oxazoline, 1-NAPHTHYLAMINE, 5,6,7,8-TETRAHYDRO-2,3-DIMETHYL-N-(2-OXAZOLINYL)-, 102280-58-0. CAS No. 102280-58-0. Molecular formula: C15H20N2O. Mole weight: 244.332 g/mol. Purity: 0.96. IUPACName: N-(2,3-dimethyl-5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1,3-oxazol-2-amine. Canonical SMILES: CC1=C(C(=C2CCCCC2=C1)NC3=NCCO3)C. Density: 1.2g/cm³. Catalog: ACM102280580. Alfa Chemistry. 3
N-Ethyl-1-naphthylamine N-Ethyl-1-naphthylamine is used as a reagent in the synthesis of 5,6,7,8-tetrahydroquinoline C5a receptor antagonists. Also used as a reagent in the synthesis of benzo[a]phenoxazinium chalcogen analogs as broad-spectrum antimicrobial photosensitizers. Group: Biochemicals. Grades: Highly Purified. CAS No. 118-44-5. Pack Sizes: 1g, 5g. Molecular Formula: C12H13N, Molecular Weight: 171.24. US Biological Life Sciences. USBiological 5
Worldwide
S- ( + ) -1-Aminotetra hydronaphthalene S- ( + ) -1-Aminotetra hydronaphthalene . Group: Biochemicals. Alternative Names: (S)-(+)-1,2,3,4-Tetrahydro-1-naphthylamine; (S)-(+)-1-Aminotetralin; (S)-1,2,3,4-Tetrahydro-1-naphthalenamine. Grades: Highly Purified. CAS No. 23357-52-0. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C10H13N. US Biological Life Sciences. USBiological 6
Worldwide
N-(2,4-Dibromo-5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-1-ium-2-amine bromide Heterocyclic Organic Compound. Alternative Names: 2-(2,4-Dibromo-5,6,7,8-tetrahydro-1-naphthylamino)-2-imidazoline hydrobromide, 2-IMIDAZOLINE, 2-(2,4-DIBROMO-5,6,7,8-TETRAHYDRO-1-NAPHTHYLAMINO)-, HYDROBROMIDE, 101564-94-7, 2-[(2,4-dibromo-5,6,7,8-tetrahydronaphthalen-1-yl)amino]-4,5-dihydro-1h-imidazol-1-ium bromide, AC1Q1R8C, AC1L1P80, LS-79605, N-(2,4-dibromo-5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-1-ium-2-amine bromide. CAS No. 101564-94-7. Molecular formula: C13H16Br3N3. Mole weight: 453.998 g/mol. Purity: 0.96. IUPACName: N-(2,4-dibromo-5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-1-ium-2-amine;bromide. Canonical SMILES: C1CCC2=C (C1)C (=CC (=C2NC3=NCC[NH2+]3)Br)Br. [Br-]. Catalog: ACM101564947. Alfa Chemistry. 3

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