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TG 100801 TG 100801 is a proagent that generates TG 100572 by de-esterification in development to treat age-related macular degeneration. TG 100572 is a multi-targeted kinase inhibitor which inhibits receptor tyrosine kinases and Src kinases ; has IC 50 s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1 , VEGFR2 , FGFR1 , FGFR2 , PDGFRβ , Fgr , Fyn , Hck , Lck , Lyn , Src , Yes , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 867331-82-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10186. MedChemExpress MCE
TG 100801 TG 100801 is the prodrug of TG 100572, which is a multi-targeted kinase inhibitor that inhibit select growth factor receptor tyrosine kinases and Src familt kinases. It is currently in a clinical trial as a first in class, VEGFr2 targeting, topically applied compound for the treatment of AMD. It is a new drug that inhibits ocular angiogenesis, vascular leak, and inflammation in laboratory studies. Synonyms: TG 100801; TG100801; TG-100801. Grades: >98%. CAS No. 867331-82-6. Molecular formula: C33H30ClN5O3. Mole weight: 580.08. BOC Sciences 10
TG 100801 Hydrochloride TG 100801 is the prodrug of TG 100572, which is a multi-targeted kinase inhibitor that inhibit select growth factor receptor tyrosine kinases and Src familt kinases with IC50 values of 2/7/2/1/0.5 nM or VEGFR1/VEGFR2/FGFR1/Src/Fy. Synonyms: TG 100801 Hydrochloride; TG100801 Hydrochloride; TG-100801 Hydrochloride. Grades: >98%. CAS No. 1018069-81-2. Molecular formula: C33H31Cl2N5O3. Mole weight: 616.54. BOC Sciences 10

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