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| Product | Description | |
|---|---|---|
| TG101348 | Fedratinib is a potent and selective JAK2 inhibitor with IC50 value of 6 nM. It also exhibits inhibitory effects against FLT3 (IC50 = 25 nM), RET (IC50 = 17 nM) and JAK3 (IC50 = 169 nM). Synonyms: TG101348; TG 101348; TG-101348; SAR302503; SAR-302503; SAR 302503; Fedratinib; N-tert-butyl-3-[[5-methyl-2-[4-(2-pyrrolidin-1-ylethoxy)anilino]pyrimidin-4-yl]amino]benzenesulfonamide. Grades: >98%. CAS No. 936091-26-8. Molecular formula: C27H36N6O3S. Mole weight: 524.68. |  |
| TG101348 (SAR302503) | TG101348 is a potent, and selective inhibitor of JAK2 (IC50 = 3 nM). It has a 35- and 334-fold selectivity over JAK3 and JAK1, respectively. Group: Biochemicals. Alternative Names: N-tert-butyl-3- (5-methyl-2- (4- (2- (pyrrolidin-1-yl) ethoxy) phenylamino) pyrimidin-4-ylamino) benzenesulfonamide. Grades: Highly Purified. CAS No. 936091-26-8. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
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