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| Product | Description | |
|---|---|---|
| Thiazovivin | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Thiazovivin | Thiazovivin. Group: Biochemicals. Grades: Highly Purified. CAS No. 1226056-71-8. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Thiazovivin | Thiazovivin is a potent ROCK inhibitor, which can protect human embryonic stem cells. Thiazovivin improves the efficiency of iPSC generation. Uses: Scientific research. Group: Signaling pathways. CAS No. 1226056-71-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13257. |  |
| Thiazovivin | Thiazovivin is a selective, cell permeable small molecule that directly targets Rho-associated kinase (ROCK). In addition, Thiazovivin protects human embryonic stem cells (hESCs) in the absence of ECM by regulating E-cadherin mediated cell-cell interaction. This observation suggests that Thiazovivin promotes cell survival. In other studies Thiazovivin, in combination with inhibitors of the TGF-β receptor and MEK pathway, has shown to improve reprogramming efficiency by more than 200-fold. Uses: Reprogramming, self-renewal. Synonyms: Thiazovivin; 1226056-71-8; N-benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide; Thiazovivin (GMP); N-benzyl-2-(pyrimidin-4-ylamino)-1,3-thiazole-4-carboxamide; N-Benzyl-2-(pyrimidin-4-ylamino)-thiazole-4-carboxamide; N-(PHENYLMETHYL)-2-(4-PYRIMIDINYLAMINO)-4-THIAZOLECARBOXAMIDE; N-Benzyl-[2-(pyrimidin-4-yl)amino]thiazole-4-carboxamide; 4-THIAZOLECARBOXAMIDE, N-(PHENYLMETHYL)-2-(4-PYRIMIDINYLAMINO)-; SR-01000650935; C15H13N5OS; MLS006011152; SCHEMBL669856; CHEMBL3184878; DTXSID00673091; HMS3654N10; AMY36698; EX-A1693; HB3240; HY-13257G; MFCD16495823; s1459; AKOS016010502; CCG-267592; CS-0468; NCGC00187983-01; NCGC00187983-10; AC-28391; AS-16722; HY-13257; SMR004702926; CS-0626100; FT-0675156; SW219580-1; A25616; EN300-1719578; J-004834; SR-01000650935-1; SR-01000650935-2; Z2044738962; N-Benzyl-[2-(pyrimidin-4-yl)amino]t hiazole-4-carboxamide; N-Benzyl-2-[(pyrimidin-4-yl)amino]-1,3-thiazole-4-carboxamide. Grades: 0.98. CAS No. 1226056-71-8. Molecular formula: C15H13N5OS. Mole weight: 311.363. |  |
| Thiazovivin (N-Benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide) | Cell-permeable. Helps in promoting human embryonic stem cell (hESC) survival by > 30-fold. In combination with ALK5 inhibitor SB-431542 (Cat. No. 1674-1) and MEK inhibitor PD- 0325901 (Cat. No. 1643-2), Thiazovivin promotes the transformation of fibroblasts into stem cells with a 200-fold efficiency. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| iPSC Induction Enhancer, Thiazovivin (N-Benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide, Induced Pluripotent Stem Cells Induction Enhancer, Rho Kinase Inhibitor XII) | A cell-permeable aminothiazolo-carboxamide compound that is reported to augment SB431542 and PD0325901 in enhancing human iPSCs (induced Pluripotent Stem Cells) generation from fibroblast cultures virally transfected with 4-TF (Oct44, Klf4, Sox2, and c-Myc). Simultaneous blockage of TGFb and MEK-ERK pathways by SB431542 (2uM) and PD0325901 (0.5uM) in addition to 4-TF-induction is shown to result in >50-fold improvement of iPSCs generation, while the inclusion of Thiazovivin (0.5uM) on top of SB431542 and PD0325901 is demonstrated to further improve the efficiency to an over-all of >200-fold improvement from 4-TF-induction alone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
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