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| Product | Description | |
|---|---|---|
| thimet oligopeptidase | Thiol compounds activate at low concentrations. Type example of peptidase family M3. Group: Enzymes. Synonyms: Pz-peptidase; soluble metalloendopeptidase; endo-oligopeptidase A; tissue-endopeptidase degrading collagenase-synthetic-substrate. Enzyme Commission Number: EC 3.4.24.15. CAS No. 110639-28-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4296; thimet oligopeptidase; EC 3.4.24.15; 110639-28-6; Pz-peptidase; soluble metalloendopeptidase; endo-oligopeptidase A; tissue-endopeptidase degrading collagenase-synthetic-substrate. Cat No: EXWM-4296. |  |
| Monoclonal Anti-Thimet Oligopeptidase 1 antibody produced in mouse | 1 mg/mL, clone IVD6, purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. |  |
| Mca-Amyloid β/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide | Mca-Amyloid β/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide, a fluorescent (FRET) peptide substrate containing the wild-type amyloid precursor protein (APP) β-secretase cleavage site, is used to determine the β-secretase-like activity of thimet oligopeptidase (TOP, EC 3.4.24.15). TOP is a potential β-secretase candidate and is involved in APP processing in vivo. Synonyms: Mca-APP770 (667-676)-Lys(Dnp)-Arg-Arg amide; Mca-Ser-Glu-Val-Lys-Met-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH2; Mca-SEVKMDAEFRK(Dnp)RR-amide. Grade: ≥95% by HPLC. CAS No. 1802078-33-6. Molecular formula: C87H129N27O28S. Mole weight: 2033.21. |  |
| mitochondrial intermediate peptidase | A homologue of thimet oligopeptidase. Natural substrates are precursor proteins that have already been processed by mitochondrial processing peptidase. In peptidase family M3 (thimet oligopeptidase family). Group: Enzymes. Synonyms: mitochondrial intermediate precursor-processing proteinase; MIP. Enzyme Commission Number: EC 3.4.24.59. CAS No. 136447-30-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4341; mitochondrial intermediate peptidase; EC 3.4.24.59; 136447-30-8; mitochondrial intermediate precursor-processing proteinase; MIP. Cat No: EXWM-4341. | |
| neurolysin | No absolute requirement for a prolyl bond: the enzyme acts on some peptides, such as dynorphin 1-8, that do not contain proline, and does not act on some others that do. In peptidase family M3 (thimet oligopeptidase family). Group: Enzymes. Synonyms: neurotensin endopeptidase; endopeptidase 24.16; endo-oligopeptidase B (proline-endopeptidase). Enzyme Commission Number: EC 3.4.24.16. CAS No. 149371-24-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4297; neurolysin; EC 3.4.24.16; 149371-24-4; neurotensin endopeptidase; endopeptidase 24.16; endo-oligopeptidase B (proline-endopeptidase). Cat No: EXWM-4297. | |
| N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH | N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH is a specific inhibitor of thimet oligopeptidase (soluble metalloendopeptidase, EC 3.4.24.15) with a Ki of 0.027±0.003 μM. Neprilysin (Endopeptidase-2, EC 3.4.24.11) converts it into a potent inhibitor of angiotensin-converting enzyme (ACE). Synonyms: Cpp-AAF-pAb; Cfp-aaf-pab; N-(1-Carboxy-3-phenylpropyl)-ala-ala-phe-p-aminobenzoate; N-(1-Carboxy-3-phenylpropyl)-alanyl-alanyl-phenylalanine-4-aminobenzoate; L-Phenylalaninamide, N-(1-carboxy-3-phenylpropyl)-L-alanyl-L-alanyl-N-(4-carboxyphenyl)-; N-(1-Carboxy-3-phenylpropyl)-L-alanyl-N-{(2S)-2-[(4-carboxyphenyl)amino]-3-phenylpropanoyl}-L-alaninamide. Grade: ≥95%. CAS No. 116560-97-5. Molecular formula: C32H36N4O7. Mole weight: 588.66. | |
| oligopeptidase A | Known from Escherichia coli and Salmonella typhimurium. A zinc metallopeptidase, in peptidase family M3 (thimet oligopeptidase family), but differs from thimet oligopeptidase in lack of thiol-activation. Group: Enzymes. Synonyms: 68000-M signalpeptide hydrolase. Enzyme Commission Number: EC 3.4.24.70. CAS No. 394250-11-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4354; oligopeptidase A; EC 3.4.24.70; 394250-11-4; 68000-M signalpeptide hydrolase. Cat No: EXWM-4354. | |
| peptidyl-dipeptidase Dcp | Known from Escherichia coli and Salmonella typhimurium. A zinc metallopeptidase in peptidase family M3 (thimet oligopeptidase family). Ac-Ala?Ala-Ala is a good test substrate. Inhibited by captopril, as is peptidyl-dipeptidase A. Formerly EC 3.4.15.3, and included in EC 3.4.15.1, peptidyl-dipeptidase A. Group: Enzymes. Synonyms: dipeptidyl carboxypeptidase (Dcp); dipeptidyl carboxypeptidase. Enzyme Commission Number: EC 3.4.15.5. CAS No. 395642-28-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4055; peptidyl-dipeptidase Dcp; EC 3.4.15.5; 395642-28-1; dipeptidyl carboxypeptidase (Dcp); dipeptidyl carboxypeptidase. Cat No: EXWM-4055. | |
| PZ-Peptide | PZ-Peptide is a chromogenic substrate for the assay of collagenase and thimet oligopeptidase (Pz-peptidase, metalloendopeptidase 24.15, collagenase-like peptidase). Synonyms: 4-Phenylazobenzyloxycarbonyl-L-pro-leu-gly-pro-D-arg dihydrate; Pz-Cpz-Pro-Leu-Gly-Pro-Arg. CAS No. 17011-78-8. Molecular formula: C38H52N10O8. Mole weight: 776.88. | |
| saccharolysin | An 83 kDa cytoplasmic thiol-dependent metalloendopeptidase from Saccharomyces cerevisiae. In peptidase family M3 (thimet oligopeptidase family). Group: Enzymes. Synonyms: proteinase yscD; yeast cysteine proteinase D (Misleading); Saccharomyces cerevisiae proteinase yscD. Enzyme Commission Number: EC 3.4.24.37. CAS No. 96779-48-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4319; saccharolysin; EC 3.4.24.37; 96779-48-5; proteinase yscD; yeast cysteine proteinase D (Misleading); Saccharomyces cerevisiae proteinase yscD. Cat No: EXWM-4319. | |
| SUC-GLY-PRO-LEU-GLY-PRO-AMC | Suc-GPLGP-AMC is a highly sensitive fluorogenic substrate for thimet oligopeptidase (collagenase-like peptidase, Pz-peptidase, metalloendopeptidase 24.15) as well as for post-proline cleaving enzyme (prolyl endopeptidase). Synonyms: succinyl-Gly-Pro-Leu-Gly-Pro-4-methylcoumaryl-7-amide; N-(3-Carboxy-1-oxopropyl)glycyl-L-prolyl-L-leucylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-prolinamide. Grade: 95%. CAS No. 72698-36-3. Molecular formula: C34H44N6O10. Mole weight: 696.75. | |
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