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| Product | Description | |
|---|---|---|
| Thiolutin | from Streptomyces luteosporeus, ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Thiolutin | Thiolutin (Acetopyrrothin) is a disulfide-containing antibiotic and anti-angiogenic compound produced by Streptomyces. Thiolutin inhibits the JAMM metalloproteases Csn5, Associated-molecule-with-the-SH3-Domain-of-STAM (AMSH) and Brcc36 [1]. Thiolutin is a potent and selective inhibitor of endothelial cell adhesion accompanied by rapid induction of Heat-shock protein beta-1 (Hsp27) phosphorylation [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Acetopyrrothin. CAS No. 87-11-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N6712. |  |
| Thiolutin | Thiolutin (Acetopyrrothin) is a disulfide-containing antibiotic and anti-angiogenic compound produced by Streptomyces. Thiolutin inhibits the JAMM metalloproteases Csn5, Associated-molecule-with-the-SH3-Domain-of-STAM (AMSH) and Brcc36. Thiolutin is a potent and selective inhibitor of endothelial cell adhesion accompanied by rapid induction of Heat-shock protein beta-1 (Hsp27) phosphorylation. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 1987-11-6. Molecular formula: C8H8N2O2S2. Mole weight: 228.29. Purity: 0.9924. Canonical SMILES: CC(NC1=C2C(N(C)C1=O)=CSS2)=O. Product ID: ACM1987116. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Thiolutin | Thiolutin. Group: Biochemicals. Grades: Purified. CAS No. 87-11-6. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Thiolutin | Thiolutin is a sulfur-containing antibiotic from Streptomyces albus and Streptomyces pimprina that inhibits RNA synthesis directed by all three yeast RNA polymerase. Uses: Inhibitor of dna-primed rna polimerase and dna polimerase. apoptosis inducer. antineoplastic drug. Synonyms: Acetopyrrothin; Acetopyrrothine. Grades: >98%. CAS No. 87-11-6. Molecular formula: C8H8N2O2S2. Mole weight: 228.29. |  |
| Thiolutin (N-acetylpyrrothine, Farcinicine, Acetopyrrothine) | Thiolutin is an antibiotic first described by Tanner and co-workers in 1950. Resurgent interest in this class of microbial metabolite was stimulated by the discovery of their selective antitumor activity. Thiolutin has been shown to be a potent inhibitor of bacterial and yeast RNA polymerases and inhibitor of mannan and glucan formation in fungi. Studies have shown that thiolutin suppresses tumor cell-induced angiogenesis in vivo. Group: Biochemicals. Alternative Names: N-acetylpyrrothine, Farcinicine, Acetopyrrothine. Grades: Highly Purified. CAS No. 87-11-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Aureothricin (Propionylpyrrothione, Farcinicin, N-(4-Methyl-5-oxo-4,5-dihydro-[1,2]dithiolo[4,3-b]pyrrol-6-yl)propionamide) | Antibiotic. Active against Gram-positive and Gram-negative bacteria, yeast, filamentous fungi, protozoa and insects. Potent bacterial and yeast RNA polymerases inhibitor. Inhibitor of fungal mannan and glucan formation. Similar to thiolutin. Antitumor compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 574-95-8. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
| Aureothricin (Propionylpyrrothione, Farcinin) | Aureothricin is an antibiotic first described by Umezawa and co-workers in Japan in 1949. Resurgent interest in this class of microbial metabolites was stimulated by the discovery of their selective antitumor activity. Aureothricin is a more hydrophobic analogue of thiolutin but has received only limited attention. Members of this class, notably, thiolutin, have been shown to potent inhibitors of bacterial and yeast RNA polymerases and inhibitors of mannan and glucan formation in fungi. Studies have shown that thiolutin inhibits tumor cell-induced angiogenesis in vivo. Group: Biochemicals. Alternative Names: Propionylpyrrothione, Farcinin. Grades: Highly Purified. CAS No. 574-95-8. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
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