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3-MATIDA is a potent metabotropic glutamate (mGlu1) receptor antagonist with IC50 value of 6.3 μM at rat mGlu1a. It displays ≥ 40-fold selectivity over other receptors. It has neuroprotective activity in cultured murine cortical cells and rat hippocampal slice cultures in vitro. It reduces the volume of ischemia-induced brain infarcts in rats following systemic administration in vivo. Synonyms: α-Amino-5-carboxy-3-methyl-2-thiopheneaceticacid; 5-[amino(carboxy)methyl]-4-methylthiophene-2-carboxylic acid; 3-Methyl-aminothiophenedicarboxylicacid. Grades: ≥99% by HPLC. CAS No. 518357-51-2. Molecular formula: C8H9NO4S. Mole weight: 215.23.
Boc5
Boc5, a non-peptide glucagon-like peptide-1 (GLP-1R) receptor agonist. Synonyms: 1,3-Bis[[4-(Tert-Butoxy-Carbonylamino)Benzoyl]Amino]-2,4-Bis[3-Methoxy-4-(Thiophene-2-Carbonyloxy)-Phenyl]Cyclobutane-1,3-DicarboxylicAcid. Grades: ≥98% by HPLC. CAS No. 917569-14-3. Molecular formula: C54H52N4O16S2. Mole weight: 1077.1.
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