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| Product | Description | |
|---|---|---|
| THIP | THIP (Gaboxadol) is a selective extrasynaptic GABAA receptors ( eGABARs ) agonist (with blood-brain barrier permeability), shows an EC 50 value of 13 μM for δ-GABAAR. THIP induces strong tense GABAA -mediated currents in layer 2/3 neurons, but shows on effect on miniature IPSCs. THIP can be used in studies of sleep disorders [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Gaboxadol. CAS No. 64603-91-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10232. |  |
| THIP hydrochloride | THIP hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 85118-33-8. Pack Sizes: 50mg. US Biological Life Sciences. |  Worldwide |
| 5-Methyl-thiphene-2-isocyanate | 5-Methyl-thiphene-2-isocyanate. Group: Biochemicals. Grades: Highly Purified. CAS No. 76536-99-7. Pack Sizes: 250mg. Molecular Formula: C6H5NOS, Molecular Weight: 139.169999999999. US Biological Life Sciences. | Worldwide |
| 3,3-Dimethyl-7-oxo-6-[(2-phenylsulfanylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid | 3,3-Dimethyl-7-oxo-6-[(2-phenylsulfanylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Thiphencillin potassium, Thiphencillin potassium (USAN), 4803-45-6, SureCN192903, CHEMBL2107482, D06113. Product Category: Heterocyclic Organic Compound. CAS No. 4803-45-6. Molecular formula: C16H18N2O4S2. Mole weight: 366.455 g/mol. Purity: 0.96. IUPACName: potassium;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylsulfanylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate. Canonical SMILES: CC1(C(N2C(S1)C(C2=O)NC(=O)CSC3=CC=CC=C3)C(=O)[O-])C.[K+]. Product ID: ACM4803456. Alfa Chemistry ISO 9001:2015 Certified. Categories: TIFENCILLIN. |  |
| AGI-6780 | AGI-6780. Group: Biochemicals. Alternative Names: N-Cyclopropyl-4- (thiphen-3-yl) -3- (3- (3- (trifluoromethyl) phenyl) ureido) benzenesulfonamide. Grades: Highly Purified. CAS No. 1432660-47-3. Pack Sizes: 2.5mg. Molecular Formula: C21H18F3N3O3S2, Molecular Weight: 481.51. US Biological Life Sciences. | Worldwide |
| Gaboxadol | Gaboxadol is a GABA agonist. It was a non-opioid analgesic and a novel type of hypnotic. It was first synthesized in 1977 by the Danish chemist Povl Krogsgaard-Larsen. It is an experimental sleep aid drug developed by Lundbeck and Merck. It was used as an analgesic and anxiolytic, as well as a treatment for tardive dyskinesia, Huntington's disease, Alzheimer's disease, and spasticity. It was in clinic phase 3 trials, but now it was terminated. Uses: Gaboxadol was used as an analgesic and anxiolytic, as well as a treatment for tardive dyskinesia, huntington's disease, alzheimer's disease, and spasticity. Synonyms: OV-101;Lu-02-030;MK-0928;Lu-02030;MK0928;Lu02030;THIP;4,5,6,7-Tetrahydroisoxazolo(5,4-c)pyridin-3(2H)-one;4,5,6,7-Tetrahydro-[1,2]oxazolo[5,4-c]pyridin-6-ium-3-one. Grades: 98%. CAS No. 64603-91-4. Molecular formula: C6H8N2O2. Mole weight: 140.14. |  |
| Gaboxadol hydrochloride | Gaboxadol hydrochloride (Lu 02-030 hydrochloride) is a potent agonist of the GABA A receptor and an antagonist of GABA C receptors ( IC 50 =25 μM). Gaboxadol hydrochloride displays a partial agonist efficacy on subunit α1β2γ2 with an ED 50 value of 143 μM, a full agonist efficacy at α5 subunit ( ED 50 =28-129 μM) and a superagonist efficacy at α4β3δ ( ED 50 =6 μM). Gaboxadol hydrochloride is a non-opioid agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu 02-030 hydrochloride; THIP hydrochloride. CAS No. 85118-33-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10233. | |
| Gaboxadol hydrochloride | THIP hydrochloride is a GABAA receptor agonist and GABAA-ρ receptor antagonist. THIP exhibits antinociceptive, anticonvulsant and sedative effects. It is used as a hypnotic agent for the treatment of patients with insomnia. Uses: Hypnotic. Synonyms: THIP hydrochloride; Gaboxadol HCl. Grades: ≥ 98 % by HPLC. CAS No. 85118-33-8. Molecular formula: C6H8N2O2 · HCl. Mole weight: 176.60. | |
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