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| Product | Description | |
|---|---|---|
| THIQ | THIQ. Group: Biochemicals. Grades: Purified. CAS No. 312637-48-2. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| THIQ | THIQ is a potent and selective melanocortin 4 receptor agonist (2,3) (IC50= 1.2, 761 and 2067 nM for human MC4, MC3 and MC1 receptors respectively). Synonyms: (3R)-N-[(1R)-1-[(4-Chlorophenyl)methyl]-2-[4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidinyl]-2-oxoethyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide. Grades: > 95%. CAS No. 312637-48-2. Molecular formula: C33H41ClN6O2. Mole weight: 589.19. |  |
| THIQ | THIQ is the first selective agonist of the melanocortin-4 receptor (MC4R) , with high affinity and potency for hMC4R ( IC 50 =1.2 nM, EC 50 =2.1 nM) and rMC4R ( IC 50 =0.6 nM, EC 50 =2.9 nM). THIQ maintains low potency at MC1R, MC3R and MC5R. THIQ plays a role in eliciting erectile activity in rodents. THIQ acts as a pharmacoperone of the MC4R rescuing the cell surface expression and signaling of some intracellularly retained MC4R mutants [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312637-48-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10624. |  |
| (3R)-N-[(2R)-3-(4-Chlorophenyl)-1-[4-cyclohexyl-4-(1,2,4-triazol-1-ylmethyl)piperidin-1-yl]-1-oxopropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide | (3R)-N-[(2R)-3-(4-Chlorophenyl)-1-[4-cyclohexyl-4-(1,2,4-triazol-1-ylmethyl)piperidin-1-yl]-1-oxopropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SureCN7692116, CTK8D3680, 6-benzyl-6,7-dihydropyrrolo[3,4-b]pyridin-5-one, 109439-42-1. Product Category: Heterocyclic Organic Compound. CAS No. 109439-42-1. Molecular formula: C33H41ClN6O2. Mole weight: 589.17064 [g/mol]. Purity: 0.96. IUPACName: 6-benzyl-7H-pyrrolo[3,4-b]pyridin-5-one. Canonical SMILES: C1C2=C(C=CC=N2)C(=O)N1CC3=CC=CC=C3. Product ID: ACM109439421. Alfa Chemistry ISO 9001:2015 Certified. Categories: THIQ. |  |
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