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| Product | Description | |
|---|---|---|
| THZ1 | THZ1 Inhibitor. Uses: Scientific use. Product Category: T3664. CAS No. 1604810-83-4. |  |
| THZ1 | THZ1 is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM. THZ1 also inhibits the closely related kinases CDK12 and CDK13 and downregulates MYC expression[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1604810-83-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-80013. |  |
| THZ1 Hydrochloride | THZ1 Hydrochloride is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM. THZ1 Hydrochloride also inhibits the closely related kinases CDK12 and CDK13 and downregulates MYC expression[1][2]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-80013A. | |
| bio-THZ1 | bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7. THZ1 is a potent and selective covalent CDK7 inhibitor with an IC50 of 3.2 nM. Synonyms: (2E)-N-{4-[(3-{[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino}phenyl)carbamoyl]phenyl}-5-methyl-10,24-dioxo-28-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-14,17,20-trioxa-5,9,11,23-tetraazaoctacos-2-en-1-amide; 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[(2E)-1-[[4-[[[3-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]amino]carbonyl]phenyl]amino]-5-methyl-1,10-dioxo-14,17,20-trioxa-5,9,11-triazadocos-2-en-22-yl]hexahydro-2-oxo-, (3aS,4S,6aR)-. Grade: ≥98%. CAS No. 1604811-14-4. Molecular formula: C52H65ClN12O8S. Mole weight: 1053.67. |  |
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