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Tipiracil, a thymidine phosphorylase (TPase) inhibitor, has been found to be a potential drug candidate for metastatic colorectal cancer. Synonyms: TAS-102; TAS102. CAS No. 183204-74-2. Molecular formula: C9H11ClN4O2. Mole weight: 242.67.
Tipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical trials. TAS-102 consists of the cytotoxin Trifluridine and the thymidine phosphorylase inhibitor (TPI) tipiracil. Trifluridine is incorporated into DNA during DNA synthesis and inhibits tumor cell growth. Tipiracil protects trifluridine from being broken down when taken orally. Synonyms: Tipiracil, TPI. Grades: 0.99. CAS No. 183204-72-0. Molecular formula: C9H12Cl2N4O2. Mole weight: 279.121.
Tipiracil hydrochloride
Tipiracil (hydrochloride) is a thymidine phosphorylase inhibitor (TPI), used for cancer research. Uses: Scientific research. Group: Signaling pathways. CAS No. 183204-72-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-A0063.
Tipiracil Impurity 1
One of the impurities of Tipiracil, which is a thymidine phosphorylase (TPase) inhibitor and has been found to be a potential drug candidate for metastatic colorectal cancer. Molecular formula: C9H10ClN3O3. Mole weight: 243.65.
Tipiracil Impurity 2
One of the impurities of Tipiracil, which is a thymidine phosphorylase (TPase) inhibitor and has been found to be a potential drug candidate for metastatic colorectal cancer. Molecular formula: C6H7ClN2O3. Mole weight: 190.59.
Tipiracil Impurity 3
An impurity of Trifluridine. Trifluridine is a nucleoside analogue antiviral and nucleoside metabolic inhibitor used for the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HERPES SIMPLEX virus. Synonyms: Trifluridine Impurity 5; Methyl 5-chloro-2,6-dihydroxy-4-pyrimidinecarboxylate; Methyl 5-chloro-2,6-dihydroxypyrimidine-4-carboxylate; CD-0006; AK162189. CAS No. 91447-90-4. Molecular formula: C6H5ClN2O4. Mole weight: 204.57.
One of the impurities of Tipiracil, which is a thymidine phosphorylase (TPase) inhibitor and has been found to be a potential drug candidate for metastatic colorectal cancer. Synonyms: Tipiracil Impurity C. Grades: ≥95%. CAS No. 2101241-71-6. Molecular formula: C9H12ClN3O3. Mole weight: 245.66.
One of the impurities of Tipiracil, which is a thymidine phosphorylase (TPase) inhibitor and has been found to be a potential drug candidate for metastatic colorectal cancer. Synonyms: Tipiracil Impurity des Cl. Grades: ≥95%. CAS No. 2069937-25-1. Molecular formula: C9H12N4O2. Mole weight: 208.22.
TAS-102
TAS-102 is a combination drug composed of the cytotoxic pyrimidine analog Trifluridine (5-trifluoro-2'-deoxythymidine or TFT) and a thymidine phosphorylase inhibitor (TPI) tipiracil hydrochloride, in a molar ratio of 1.0:0.5 (TFT:TPI). TAS-102 is used as a third- or fourth-line treatment of metastatic colorectal cancer. Synonyms: Tipiracil / Trifluridine; Viroptic mixture with 5-CIMU; TAS 102; EX-A1755; Tipiracil hydrochloride / Trifluridine. CAS No. 733030-01-8. Molecular formula: C9H11ClN4O2·HCl·C10H11F3N2O5. Mole weight: 575.328.
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