Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Tirabrutinib | Tirabrutinib (ONO-4059) is an orally active Brutons Tyrosine Kinase ( BTK ) inhibitor (can cross the blood-brain barrier (BBB)), with an IC 50 of 6.8 nM. Tirabrutinib irreversibly and covalently binds to BTK and inhibits aberrant B cell receptor signaling. Tirabrutinib can be used in studies of autoimmune diseases and hematological malignancies [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ONO-4059; GS-4059. CAS No. 1351636-18-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15771. |  |
| Tirabrutinib hydrochloride | Tirabrutinib (ONO-4059) hydrochloride is an orally active Brutons Tyrosine Kinase ( BTK ) inhibitor (can cross the blood-brain barrier (BBB)), with an IC 50 of 6.8 nM. Tirabrutinib hydrochloride irreversibly and covalently binds to BTK and inhibits aberrant B cell receptor signaling. Tirabrutinib hydrochloride can be used in studies of autoimmune diseases and hematological malignancies [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ONO-4059 hydrochloride; GS-4059 hydrochloride. CAS No. 1439901-97-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15771A. | |
| ONO-4059 | ONO-4059, a BTK inhibitor, has been found to have potential effect against sorts of malignancies by influencing the B-cell development. It is currently under Phase II trail to study its effect against Chronic lymphocytic leukaemia. IC50: 2.2 nM. Synonyms: (R)-6-amino-9-(1-(but-2-ynoyl)pyrrolidin-3-yl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one; ONO-4059; ONO4059; ONO 4059; ONO-4059; GS 4059; GS-4059; GS4059; ONO-WG-307; Tirabrutinib. Grades: 98%. CAS No. 1351636-18-4. Molecular formula: C25H22N6O3. Mole weight: 454.48. |  |
| ONO-4059 (hydrochloride) | ONO-4059 (hydrochloride) is the hydrochloride salt form of Tirabrutinib. ONO-4059 is a highly selective, orally bioavailable BTK inhibitor (IC50= 2.2 nM) and demonstrated therapeutic efficacy in a mouse arthritis model. Synonyms: (R)-6-amino-9-(1-(but-2-ynoyl)pyrrolidin-3-yl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one hydrochloride; ONO-4059 HCl; ONO4059; ONO 4059; ONO-4059; GS 4059; GS-4059; GS4059; ONO-WG-307; Tirabrutinib. CAS No. 1439901-97-9. Molecular formula: C25H23ClN6O3. Mole weight: 490.95. | |
Our database is helping our users find suppliers everyday.
