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Tmcb TMCB is a selective, ATP-competitive CK2 (casein kinase II) inhibitor with distinct Ki values of 83 nM and 21 nM for the two different catalytic CK2 subunits α and α', respectively. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBL1233807, SureCN1759230, ABP000318, [4,5,6,7-Tetrabromo-2-(Dimethylamino)-1h-Benzimidazol-1-Yl]acetic Acid, 905105-89-7, K66. Product Category: Inhibitors. CAS No. 905105-89-7. Molecular formula: C11H9Br4N3O2. Mole weight: C11H9Br4N3O2. Purity: >98 %. IUPACName: 2-[4,5,6,7-tetrabromo-2-(dimethylamino)benzimidazol-1-yl]acetic acid. Canonical SMILES: CN(C)C1=NC2=C(N1CC(=O)O)C(=C(C(=C2Br)Br)Br)Br. Product ID: ACM905105897. Alfa Chemistry — ISO 9001:2015 Certified. Categories: TMC Bulldogs. Alfa Chemistry.
TMCB TMCB. Group: Biochemicals. Grades: Purified. CAS No. 905105-89-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TMCB TMCB is a dual-kinase inhibitor of both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8) (IC50 = 0.50 μM for both CK2 and ERK8). TMCB exhibits selectivity for CK2 over protein kinases normally susceptible to CK2 inhibitors (Ki = 0.25, 8.65, 11.90 and 15.25 μM for CK2, PIM1, DYRK1a and HIPK2, respectively). Synonyms: 2-(4,5,6,7-Tetrabromo-2-(dimethylamino)-1H-benzo[d]imidazol-1-yl)acetic acid. Grades: ≥98% by HPLC. CAS No. 905105-89-7. Molecular formula: C11H9Br4N3O2. Mole weight: 534.82. BOC Sciences 11
Casein Kinase II Inhibitor VI, TMCB - CAS 905105-89-7 The Casein Kinase II Inhibitor VI, TMCB, also referenced under CAS 905105-89-7, controls the biological activity of Casein Kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3

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