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| Product | Description | |
|---|---|---|
| TNKS656 | NVP-TNKS656, also known as TNKS656, is a potent and orally active Tankyrase Inhibitor. With an enthalpy-driven thermodynamic signature of binding, highly favorable physicochemical properties, and high lipophilic efficiency, NVP-TNKS656 is well suited for further in vivo validation studies. Bioactivity of TNKS656: TNKS2 IC50=6nM, LiPE=7.0, HEK298 STF IC50=3.5nM, Cmax/ Cellular IC50=23,000. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NVP-TNKS656; NVP-TNKS-656;NVP-TNKS 656;TNKS656; TNKS-656; TNKS 656. Product Category: Inhibitors. Appearance: solid powder. CAS No. 1419949-20-4. Molecular formula: C27H34N4O5. Mole weight: 494.58. Purity: >98%. IUPACName: N-(cyclopropylmethyl)-2-(4-(4-methoxybenzoyl)piperidin-1-yl)-N-((4-oxo-4,5,7,8-tetrahydro-3H-pyrano[4,3-d]pyrimidin-2-yl)methyl)acetamide. Canonical SMILES: O=C1NC(CN(CC2CC2)C(CN3CCC(C(C4=CC=C(OC)C=C4)=O)CC3)=O)=NC5=C1COCC5. Product ID: ACM1419949204. Alfa Chemistry ISO 9001:2015 Certified. |  |
| TNKS656 | TNKS656, also known as NVP-TNKS656, is a potent and orally active Tankyrase Inhibitor. With an enthalpy-driven thermodynamic signature of binding, highly favorable physicochemical properties, and high lipophilic efficiency, TNKS656 is well suited for further in vivo validation studies. Synonyms: NVP-TNKS656; TNKS-656. Grades: 98%. CAS No. 1419949-20-4. Molecular formula: C27H34N4O5. Mole weight: 494.592. |  |
| NVP-TNKS656 | NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC 50 of 6 nM, and is > 300 fold selectivity against PARP1 and PARP2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TNKS656. CAS No. 1419949-20-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13990. |  |
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