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| Product | Description | |
|---|---|---|
| TNP-470 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| TNP-470 | TNP-470 is a methionine aminopeptidase-2 inhibitor and also an angiogenesis inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AGM-1470. CAS No. 129298-91-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-101932. |  |
| TNP-470 | TNP-470 is an analog of fumagillin, an antimicrobial agent isolated from the fungus Aspergillus fumigatus. TNP-470 was shown to inhibit angiogenesis, and irreversibly suppress methionine aminopeptidase-2 (MetAP2). Uses: Angiogenesis inhibitors. Synonyms: AGM-1470; O-(Chloroacetyl-carbamoyl) Fumagillol; NSC 642492. Grades: ≥98%. CAS No. 129298-91-5. Molecular formula: C19H28ClNO6. Mole weight: 401.9. |  |
| TNP-470 (AGM-1470, O-(Chloroacetyl-carbamoyl)fumagillol, AGM1470, MetAP-2 Inhibitor II, MetAP2 Inhibitor II, Methionine Aminopeptidase 2 Inhibitor II, TNP470) | A cell-permeable Fumagillin analog that inhibits MetAP2, but not MetAP1, methionine aminopeptidase activity (IC50 = 1nM against human MetAP2), without affecting the inhibitory activity of MetAP2 against HRI- (heme-regulated inhibitor kinase) catalyzed eIF-2alpha phosphorylation. A potent endothelial cytostasis inducer (IC50 = 25 pM and 37 pM, respectively, against HUVEC and bovine BAEC) in vitro and an effective anti-angiogenesis agent in vivo (2-100mg/kg in mice and rats; s.c.). Group: Biochemicals. Grades: Highly Purified. CAS No. 129298-91-5. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
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