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| Product | Description | |
|---|---|---|
| tocilizumab | Tocilizumab is a humanized monoclonal antibody resistant against the interleukin-6 receptor (IL-6R). It is an immunosuppressive agent commonly used for the treatment of rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis. Actemra (tocilizumab) 162 mg syringe for subcutaneous injection and Actemra 162 mg auto-injector for subcutaneous injection was approved in Japan for the treatment of Takayasu arteritis (TAK) and giant cell arteritis (GCA), as well as its intravenous injection was approved by FDA for severe cytokine release syndrome (CRS). Uses: The treatment of rheumatoid arthritis (ra), systemic juvenile idiopathic arthritis, takayasu arteritis (tak), giant cell arteritis (gca), severe cytokine release syndrome (crs), etc. Synonyms: Anti-Human IL6R, Humanized Antibody; Actemra; R 1569; RoActemra; Atlizumab; Actemra 200; R1569; R-1569. Grades: ≥95%. CAS No. 375823-41-9. Molecular formula: C6428H9976N1720O2018S42. Mole weight: 145000. |  |
| Tocilizumab | Tocilizumab (Anti-Human IL6R, Humanized Antibody) is an anti-human interleukin-6 receptor ( IL-6R ) neutralizing antibody, prevents binding of IL-6 to the IL-6R, thereby inhibiting both classic and trans-signaling. Tocilizumab (Anti-Human IL6R, Humanized Antibody) can be used for the treatment of rheumatoid arthritis [1]. Tocilizumab is remarkablely effective for the study of severe COVID-19 (coronavirus disease) [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human IL6R, Humanized Antibody. CAS No. 375823-41-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9917. |  |
| Tocilizumab | Tocilizumab Inhibitor. Uses: Scientific use. Product Category: T9911. CAS No. 375823-41-9. |  |
| LP99 | LP99 is the first selective BRD7/9 bromodomain inhibitor. The effect of LP99 on IL-6 expression demonstrates for the first time that a small-molecule BRD7/9 inhibitor may have a similar function and utility to IL-6 neutralizing antibodies, such as tocilizumab, in the treatment of rheumatoid arthritis. Synonyms: N-[(2R,3S)-2-(4-chlorophenyl)-1-(1,4-dimethyl-2-oxoquinolin-7-yl)-6-oxopiperidin-3-yl]-2-methylpropane-1-sulfonamideN-((2R,3S)-2-(4-chlorophenyl)-1-(1,4-dimethyl-2-oxo-1,2-dihydroquinolin-7-yl)-6-oxopiperidin-3-yl)-2-methylpropane-1-sulfonamideN-[(2R,3S)-2-(4-chlorophenyl)-1-(1,4-dimethyl-2-oxo-1,2-dihydroquinolin-7-yl)-6-oxopiperidin-3-yl]-2-methylpropane-1-sulfonamideGTPL8572; GTPL 8572; GTPL-8572; LP99; LP-99; LP 99. Grades: >98%. CAS No. 1808951-93-0. Molecular formula: C26H30ClN3O4S. Mole weight: 516.05. | |
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