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| Product | Description | |
|---|---|---|
| TPMPA | TPMPA, a hybrid of isoguvacine and 3-APMPA, is the first selective antagonist for a GABA C receptor ( K B = 2.1 μM), but not to interact with GABA A ( K B = 320 μM) or GABA B receptors ( EC 50 = 500 μM). TPMPA has the potential for the research of suppressing orientation selectivity in ganglion cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 182485-36-5. Pack Sizes: 10 mg. Product ID: HY-101359. |  |
| TPMPA | TPMPA. Group: Biochemicals. Grades: Purified. CAS No. 182485-36-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| TPMPA | TPMPA is a selective and competitive GABAA-ρ antagonist with 8-fold selectivity for human recombinant ρ1 receptors over ρ2 receptors. TPMPA exhibits minimal effects on GABAA and GABAB receptors (Kb = 2.1 μM (antagonist), 320 μM (antagonist) and EC50 ~ 500 μM (weak agonist) for GABAA-ρ, GABAA and GABAB receptors, respectively). Synonyms: (1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid; methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid. Grades: ≥98% by HPLC. CAS No. 182485-36-5. Molecular formula: C6H12NO2P. Mole weight: 161.14. |  |
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