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| Product | Description | |
|---|---|---|
| TQS | TQS. Group: Biochemicals. Grades: Purified. CAS No. 353483-92-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| TQS | TQS is a α7 nicotinic acetylcholine receptor ( nAChR ) positive allosteric modulator. TQS can be used for the research of neuroinflammatory pain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 353483-92-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107682. |  |
| TQS | TQS is a type II positive allosteric modulator of α7 nACh receptors (pEC50 = 5.5) with no activity at α7 receptors at concentrations up to 0.1 mM. TQS potentiates agonist-evoked responses and reduces rate of desensitization of α7 nAChRs. Synonyms: 3a,4,5,9b-Tetrahydro-4-(1-naphthalenyl)-3H-cyclopentan[c]quinoline-8-sulfonamide. Grades: ≥98% by HPLC. CAS No. 353483-92-8. Molecular formula: C22H20N2O2S. Mole weight: 376.47. |  |
| 4BP-TQS | 4BP-TQS. Group: Biochemicals. Grades: Purified. CAS No. 360791-49-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 4BP-TQS | 4BP-TQS is an allosteric agonist of α7 nicotinic acetylcholine receptors (nAChR). It binds to an allosteric transmembrane site, and exhibits a more potent and efficacious agonism at α7 nAChR than ACh (8-fold lower EC50 and 45-fold larger maximal response). Synonyms: 4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide; ST042158; 4-(4-bromophenyl)-3H,3aH,4H,5H,9bH-cyclopenta[c]quinoline-8-sulfonamide; AC1MEMT7. Grades: 99%. CAS No. 360791-49-7. Molecular formula: C18H17BrN2O2S. Mole weight: 405.31. | |
| 4BP-TQS | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| GAT107 | GAT107 is an allosteric agonist (EC50 value 28 μM) and positive allosteric modulator (PAM) of α7 nicotinic acetylcholine receptors (nAChR). GAT107 is the bioactive enantiomer of 4BP-TQS. It reverses nociception in mouse models of inflammatory and neuropathic pain. Synonyms: GAT107; GAT-107; GAT 107; (3aR,4S,9bS)-4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide. Grades: 99%. CAS No. 1476807-74-5. Molecular formula: C18H17BrN2O2S. Mole weight: 405.31. | |
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