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TRAM 39 TRAM 39. Group: Biochemicals. Grades: Purified. CAS No. 197525-99-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TRAM 39 TRAM 39 is a potent intermediate conductance Ca2+-activated K+ channel (KCa3.1) blocker (Kd = 60 nM) with no effect on cytochrome p450 activity. TRAM 39 has been shown to inhibit I-EBIO-stimulated increases in rat artery membrane potential ex vivo, and also reduce LPS-induced cryptidin (mammalian α-defensin) release from paneth cells in vitro. Synonyms: TRAM39; TRAM-39; TRAM 39; 2-Chloro-α,α-diphenylbenzeneacetonitrile. Grades: ≥99% by HPLC. CAS No. 197525-99-8. Molecular formula: C20H14ClN. Mole weight: 303.78. BOC Sciences 10

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