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| Product | Description | |
|---|---|---|
| trans-Ned-19 | trans-Ned-19 is a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. trans-Ned-19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM) and also inhibits [32P]NAADP binding (IC50 = 0.4 nM). trans-Ned-19 can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells. Group: Biochemicals. Alternative Names: (1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole-3-carboxylic Acid. Grades: Highly Purified. CAS No. 1354235-96-3. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| trans-Ned-19 Methyl Ester | trans-Ned-19 Methyl Ester is a trans-Ned-19 (N388750) derivative, a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. Group: Biochemicals. Alternative Names: (1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 3-[[4-(2-Fluorophenyl)-1-piperazinyl]methyl]-4-methoxy-benzaldehyde | 3-[[4-(2-Fluorophenyl)-1-piperazinyl]methyl]-4-methoxy-benzaldehyde is a piperazine derivative used in the preparation of trans-Ned-19 (N388750). Group: Biochemicals. Grades: Highly Purified. CAS No. 933916-93-9. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| cis-Ned-19 Methyl Ester | cis-Ned-19 Methyl Ester is a side product produced during the preparation of trans-Ned-19 (N388750), a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. Group: Biochemicals. Alternative Names: (1R,3R)-1-[3-[[4-(2-Fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| trans-Ned 19 | trans-Ned 19, a structural analog of NAADP, is a nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist.trans-Ned 19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM), and also inhibits [32P]NAADP binding (IC50 = 0.4 nM). It can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells. Synonyms: (1R,3S)-1-[3-[[4-(2-Fluorophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid; Ned-19; Ned 19; Ned19. Grades: ≥98% by HPLC. CAS No. 1354235-96-3. Molecular formula: C30H31FN4O3. Mole weight: 514.59. |  |
| trans-Ned 19 | trans-Ned 19. Group: Biochemicals. Grades: Purified. CAS No. 1354235-96-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| trans-Ned 19 | trans-Ned 19 is a NAADP antagonist and TPC blocker. trans-Ned 19 suppresses the calcium signal and the rat aorta relaxation in response to low histamine concentrations. trans-Ned 19 increases the spontaneous acrosome reaction rate, alleviates anti-CD3 mAb-induced intestinal inflammation, and improves kidney damage in mice with nephrotoxic serum nephritis [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1354235-96-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-103316. |  |
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