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Tretazicar Tretazicar (CB 1954), an antitumor proagent, is highly selective against the Walker 256 rat tumour line. Tretazicar is enzymatically activated to generate a bifunctional agent, which can form DNA-DNA interstrand cross-links. Tretazicar in rat cells involves the reduction of its 4-nitro group to a 4-hydroxylamine by the enzyme NAD(P)H:quinone oxidoreductase 1 (NQO1) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CB 1954. CAS No. 21919-05-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13543. MedChemExpress MCE
Tretazicar Tretazicar is an anticancer prodrug used in gene therapy research and is known to be activated by NAD(P)H Quinone Oxidoreductase 2. Group: Biochemicals. Alternative Names: 5-(1-Aziridinyl)-2,4-dinitrobenzamide; 2, 4-Dinitro-5-ethylene iminobenzamide; 2, 4-Dinitroethylene iminobenzamide; 5-(1-Aziridinyl)-2,4-dinitrobenzamide; 5-Aziridino-2,4-dinitrobenzamide; 5-Aziridinyl-2,4-dinitrobenzamide; CB 1954; NSC 115829. Grades: Highly Purified. CAS No. 21919-05-1. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
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