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| Product | Description | |
|---|---|---|
| Trihydroxycoprostane | A sterol, similar to cholesterol and is a substrate for the sterol 27-hydroxylase enzyme in the bile salt synthetic pathway. The accumulation of this compound in urine can manifest as jaundice or, in more extreme cases, is a sign of Xanthomatosis. Group: Biochemicals. Alternative Names: (3α,5 β, 7α, 12α)-Cholestane-3, 7, 12-triol; 3α, 7α, 12α-Trihydroxycoprostane. Grades: Highly Purified. CAS No. 547-96-6. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Trihydroxycoprostane | Trihydroxycoprostane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (3alpha,5beta,7alpha,12alpha)-Cholestane-3,7,12-triol; 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane; (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol; 5beta-cholestan-3alpha,7alpha,12alpha-triol; 5beta-Cholestane-3alpha,7alpha,12alpha-triol; (3|A,5|A,7|A,12|A)-cholestane-3,7,12-triol; 3alpha,7alpha,12alpha-Trihydroxycoprostane; Trihydroxycoprostane; 5beta-cholestane-3alpha,7alpha,12alpha-triol. Product Category: Steroidal Compounds. CAS No. 547-96-6. Molecular formula: C27H48O3. Mole weight: 420.67. Purity: 0.95. IUPACName: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol. Canonical SMILES: CC(C)CCCC(C)C1CCC2[C@@H]3C(O)C[C@@H]4CC(O)CC[C@H]4(C)C3CC(O)[C@H]12C. Density: 1.051g/cm³. Product ID: ACM547966. Alfa Chemistry ISO 9001:2015 Certified. Categories: Trihydroxycoprostanoyl-CoA synthetase. |  |
| Trihydroxycoprostane 3,7,12-Triethoxymethyl Ether | Protected Trihydroxycoprostane. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 24-Phenylsulfonyl-5 β-Cholane-3α, 7α, 12α-triol 3,7,12-Triethoxymethyl Ether | 24-Phenylsulfonyl-5 β-Cholane-3α, 7α, 12α-triol 3,7,12-Triethoxymethyl Ether is an intermediate of Trihydroxycoprostane (T795150), a sterol similar to cholesterol and is a substrate for the sterol 27-hydroxylase enzyme in the bile salt synthetic pathway. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C39H64O8S, Molecular Weight: 692.99. US Biological Life Sciences. | Worldwide |
| 3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA 24-hydroxylase | Requires ATP. The reaction in mammals possibly involves dehydrogenation to give a 24(25)-double bond followed by hydration. However, in amphibians such as the Oriental fire-bellied toad (Bombina orientalis), it is probable that the product is formed via direct hydroxylation of the saturated side chain of (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate and not via hydration of a 24(25) double bond. In microsomes, the free acid is preferred to the coenzyme A ester, whereas in mitochondria, the coenzyme A ester is preferred to the free-acid form of the substrate. Group: Enzymes. Synonyms: trihydroxycoprostanoyl-CoA oxidase; THC-CoA oxidase; THCA-CoA oxidase; 3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA oxidase; 3α,. Enzyme Commission Number: EC 1.17.99.3. CAS No. 119799-47-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1103; 3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA 24-hydroxylase; EC 1.17.99.3; 119799-47-2; trihydroxycoprostanoyl-CoA oxidase; THC-CoA oxidase; THCA-CoA oxidase; 3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA oxidase; 3α,7α,12α-trihydroxy-5β-cholestan-26-oate 24-hydroxylase. Cat No: EXWM-1103. |  |
| α-methylacyl-CoA racemase | α-methyl-branched acyl-CoA derivatives with chain lengths of more than C10 are substrates. Also active towards some aromatic compounds (e.g. ibuprofen) and bile acid intermediates, such as trihydroxycoprostanoyl-CoA. Not active towards free acids. Group: Enzymes. Enzyme Commission Number: EC 5.1.99.4. CAS No. 156681-44-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5436; α-methylacyl-CoA racemase; EC 5.1.99.4; 156681-44-6. Cat No: EXWM-5436. | |
| cholate-CoA ligase | Requires Mg2+ for activity. The mammalian enzyme is membrane-bound and catalyses the first step in the conjugation of bile acids with amino acids, converting bile acids into their acyl-CoA thioesters. Chenodeoxycholate, deoxycholate, lithocholate and trihydroxycoprostanoate can also act as substrates. The bacterial enzyme is soluble and participates in an anaerobic bile acid 7 α-dehydroxylation pathway. Group: Enzymes. Synonyms: BAL; bile acid CoA ligase; bile acid co. Enzyme Commission Number: EC 6.2.1.7. CAS No. 9027-90-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5709; cholate-CoA ligase; EC 6.2.1.7; 9027-90-1; BAL; bile acid CoA ligase; bile acid coenzyme A ligase; choloyl-CoA synthetase; choloyl coenzyme A synthetase; cholic thiokinase; cholate thiokinase; cholic acid:CoA ligase; 3α,7α,12α-trihydroxy-5β-cholestanoyl coenzyme A synthetase; 3α,7α,12α-trihydroxy-5β-cholestanoate-CoA ligase; 3α,7α,12α-trihydroxy-5β-cholestanoate-CoA synthetase; THCA-CoA ligase; 3α,7α,12α-trihydroxy-5β-cholestanate-CoA ligase; 3α,7α,12α-trihydroxy-5β-cholestanate:CoA ligase (AMP-forming); cholyl-CoA synthetase; trihydroxycoprostanoyl-CoA synthetase. Cat No: EXWM-5709. | |
| choloyl-CoA hydrolase | Also acts on chenodeoxycholoyl-CoA and to a lesser extent on short- and medium- to long-chain acyl-CoAs, and other substrates, including trihydroxycoprostanoyl-CoA, hydroxymethylglutaryl-CoA and branched chain acyl-CoAs, all of which are present in peroxisomes. The enzyme is strongly inhibited by CoA and may be involved in controlling CoA levels in the peroxisome. Group: Enzymes. Synonyms: PTE-2 (ambiguous); choloyl-coenzyme A thioesterase; chenodeoxycholoyl-coenzyme A thioesterase; peroxisomal acyl-CoA thioesterase 2. Enzyme Commission Number: EC 3.1.2.27. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3560; choloyl-CoA hydrolase; EC 3.1.2.27; PTE-2 (ambiguous); choloyl-coenzyme A thioesterase; chenodeoxycholoyl-coenzyme A thioesterase; peroxisomal acyl-CoA thioesterase 2. Cat No: EXWM-3560. | |
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