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TMAO (TMAO) is the organic compound in the class of amine oxides with the formula (CH3)3NO. This colorless solid is usually encountered as the dihydrate. It is a product of the oxidation of trimethylamine and a common metabolite in animals. It is an osmolyte found in saltwater fish, sharks, rays, molluscs, and crustaceans. It is a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays. It is also higher in deep-sea fishes and crustaceans, where it may counteract the protein-destabilizing effects of pressure. TMAO decomposes to trimethylamine (TMA), which is the main odorant that is characteristic of degrading seafood. Group: Heterocyclic organic compound. Alternative Names: Trimethyloxamine. CAS No. 1184-78-7. Molecular formula: C3H9NO. Mole weight: 75.11. Appearance: Pale yellow solid. Purity: 0.95. IUPACName: N,N-Dimethylmethanamine oxide. Canonical SMILES: C[N+](C)(C)[O-]. Density: 0.9301 g/cm³. ECNumber: 214-675-6. Catalog: ACM1184787.
TrimethylamineN-oxide
TrimethylamineN-oxide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1184-78-7. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C3H9NO. US Biological Life Sciences.
Worldwide
TrimethylamineN-oxide
TrimethylamineN-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. TrimethylamineN-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. TrimethylamineN-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 1184-78-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-116084.
TrimethylamineN-oxide-d9
TrimethylamineN-oxide-d 9 is the deuterium labeled TrimethylamineN-oxide. TrimethylamineN-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. TrimethylamineN-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. TrimethylamineN-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway[1][2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1161070-49-0. Pack Sizes: 1 mg. Product ID: HY-116084S.
TrimethylamineN-oxide dihydrate is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. TrimethylamineN-oxide dihydrate induces inflammation by activating the ROS/NLRP3 inflammasome. TrimethylamineN-oxide dihydrate also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 62637-93-8. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-108915.
Trimethylamine-13C3 N-Oxide
Trimethylamine-13C3 N-Oxide. Group: Biochemicals. Alternative Names: N,N-Dimethylmethanamine-13C3 N-Oxide; N,N-Di(methyl13C2 )methanamine-13C N-Oxide. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: 13C3H9NO, Molecular Weight: 78.09. US Biological Life Sciences.
Worldwide
Trimethylamine-d9 N-Oxide
Labeled TrimethylamineN-Oxide, a potential osmolyte biomarker used in the measurement of marine osmolytes in mammalian serum. Group: Biochemicals. Alternative Names: N,N-Dimethylmethanamine-d3 N-Oxide; N,N-Di(methyl-d3)methan-d3-amine N-Oxide. Grades: Highly Purified. CAS No. 1161070-49-0. Pack Sizes: 5mg. Molecular Formula: C?D?NO, Molecular Weight: 84.17. US Biological Life Sciences.
Worldwide
trimethylamine-N-oxide reductase
This enzyme belongs to the family of oxidoreductases, specifically those acting on NADH or NADPH with a nitrogenous group as acceptor. The systematic name of this enzyme class is NADH:trimethylamine-N-oxide oxidoreductase. Other names in common use include trimethylamineN-oxide reductase, trimethylamine oxide reductase, TMAO reductase, and TOR. This enzyme participates in methane metabolism. Group: Enzymes. Synonyms: trimethylamineN-oxide reductase; trimethylamine oxide reductase; TMAO reductase; TOR. Enzyme Commission Number: EC 1.6.6.9. CAS No. 37256-34-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1599; trimethylamine-N-oxide reductase; EC 1.6.6.9; 37256-34-1; trimethylamineN-oxide reductase; trimethylamine oxide reductase; TMAO reductase; TOR. Cat No: EXWM-1599.
3,3-Dimethyl-1-butanol
3,3-Dimethyl-1-butanol (DMB) is an orally active inhibitor of trimethylamine ( TMA ) and trimethylamineN-oxide ( TMAO ). 3,3-Dimethyl-1-butanol inhibits the signaling pathway of p65 NF-κB and TGF-β1/Smad3. 3,3-Dimethyl-1-butanol has potential applications in cardiovascular disease (CVD) [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: DMB; Neohexanol. CAS No. 624-95-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W012977.
delta-Valerobetaine
delta-Valerobetaine is a precursor of trimethylamineN-oxide (TMAO). Uses: Scientific research. Group: Natural products. CAS No. 6778-33-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114202.
dimethylsulfoxide reductase
Contains molybdopterin and [4Fe-4S] clusters. Also reduces pyridine N-oxide and trimethylamineN-oxide, with lower activity, to the corresponding amines. Group: Enzymes. Synonyms: DMSO reductase. Enzyme Commission Number: EC 1.8.5.3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1678; dimethylsulfoxide reductase; EC 1.8.5.3; DMSO reductase. Cat No: EXWM-1678.
trimethylamine-oxide aldolase
This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. This enzyme participates in methane metabolism. Group: Enzymes. Synonyms: trimethylamineN-oxide formaldehyde-lyase; trimethylamineN-oxide aldolase; trimethylamineN-oxide demethylase; trimethylamine-N-oxide formaldehyde-lyase. Enzyme Commission Number: EC 4.1.2.32. CAS No. 72561-08-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4869; trimethylamine-oxide aldolase; EC 4.1.2.32; 72561-08-1; trimethylamineN-oxide formaldehyde-lyase; trimethylamineN-oxide aldolase; trimethylamineN-oxide demethylase; trimethylamine-N-oxide formaldehyde-lyase. Cat No: EXWM-4869.
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