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Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. It has immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is an NF-κB activation inhibitor. Uses: Adcs cytotoxin. Synonyms: NSC 163062; PG490; Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-; (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one; (-)-Triptolide; PG 490; Triptolide. Grade: >98%. CAS No. 38748-32-2. Molecular formula: C20H24O6. Mole weight: 360.40.
Triptolide
Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: PG490. CAS No. 38748-32-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-32735.
Triptolide
Triptolide - Product ID: NST-10-187. Category: Terpenes. Purity: 98%. Test method: HPLC. CAS No. 38748-32-2. Pack Sizes: 0,05g, 0,1g, 0,25g, 0,5g. Appearance: White powder. Molecular formula: C20H24O6. Mole weight: 360.4. Storage: +2 +8 °C.
Triptolide-d3 (major, contains d0)
Labeled Triptolite , diterpenoid triepoxide with immunosuppressant and antitumor properties. Group: Biochemicals. Alternative Names: (3bS, 4aS, 5aS, 6R, 6aR, 7aS, 7bS, 8aS, 8bS)-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Triptolide Liposome (PEGylated)
Triptolide (TP) is an epoxy diterpene lactone isolated from Tripterygium wilfordii Hook. f., which has been shown to inhibit the proliferation of hepatocellular carcinoma. This product is a pre-formulated liposome encapsulating Triptolide. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
Triptolide O-Methyl Phosphate-d3 Disodium Salt
Triptolide O-Methyl Phosphate-d3 Disodium Salt. Group: Biochemicals. Alternative Names: Minnelide-d3. Grades: Highly Purified. Pack Sizes: 500ug. Molecular Formula: C21H22D3Na2O10P, Molecular Weight: 517.39. US Biological Life Sciences.
Worldwide
Triptolide O-Methyl Phosphate Disodium Salt
Triptolide (T815600) derivative. Diterpenoid triepoxide with immunosuppressant and antitumor properties. Group: Biochemicals. Alternative Names: Minnelide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Triptolide palmitate
Triptolide palmitate is the derivative of Triptolide (HY-32735). Triptolide palmitate exhibits cytotoxicity against cancer cell MCF-7 and A549, with IC 50 of 7.5 and 6.4 μM. Triptolide palmitate exhibits a half-time T 1/2 of 50.4 min in Sprague Dawley rats. Triptolide palmitate can be utilizd as drug carrier [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2126920-51-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-158090.
Triptolide (TPL)
Triptolide, a diterpenoid triepoxyde, a purified component of a traditional Chinese medicine, inhibits transcriptional activation of NF- kB and downregulates the expression of various NF- kB-regulated genes. Displays Immunosuppressive, anti-inflammatory, anti-angiogenic and antitumor activity. A combination of TRAIL and triptolide enhance apoptosis in cholangiocarcinoma cell lines. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Triptolide, Tripterygium wilfordii - CAS 38748-32-2
A novel diterpene triepoxide isolated from the Chinese herb Tripterygium wilfordii that acts as a potent immunosuppressant and anti-inflammatory agent. Group: Fluorescence/luminescence spectroscopy.
5α-Hydroxytriptolide
5α-Hydroxytriptolide is obtained from Triptolide (T815600) which is Diterpenoid triepoxide with immunosuppressant and antitumor properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 583028-68-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C20H24O7, Molecular Weight: 376.4. US Biological Life Sciences.
Worldwide
O-(Methylthio)methyl Triptolide
O-(Methylthio)methyl Triptolide is a Triptolide (T815600) derivative, used in the preparation of D-ring-modified triptolide analogues. Group: Biochemicals. Alternative Names: (3bS, 4aS, 5aR, 6R, 6aS, 7aS, 7bS, 8aS, 8bS)-b, 4, 4a, 6, 6a, 7a, 7b, 8b, 9, 10-decahydro-8b-methyl-6a-(1-methylethyl)-6-[(methylthio)methoxy]-trisoxireno[4b, 5:6, 7:8a, 9]phenanthro[1, 2-c]furan-1(3H)-one; PG 691. Grades: Highly Purified. CAS No. 847440-49-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Omtriptolide
Omtriptolide (PG490-88) is a derivative proagent of triptolide purified from the Chinese herb. Uses: Scientific research. Group: Signaling pathways. CAS No. 195883-06-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-16363.
Minnelide
Minnelide is a prodrug of triptolide that shows potent antitumor activity in a number of tumor types, particularly in pancreatic cancer. Minnelide promotes apoptosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1254702-87-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124584.
Triptonide
Triptonide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TRIPTONIDE;TRIPTONIDE(PRIMARY STANDARD);(3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-6a-Isopropyl-8b-methyl-3b,4,4a,7a,7b,8b,9,10-octahydrotrisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione;14-Deoxy-14-oxotriptolide;Triptolide,14-deoxy-14-oxo;NSC 165677;PG 492. Appearance: White-beige powder. CAS No. 38647-11-9. Molecular formula: C20H22O6. Mole weight: 358.39. Purity: 0.98. IUPACName: Triptonide. Canonical SMILES: CC(C)C12C(O1)C3C4(O3)C5(CCC6=C(C5CC7C4(C2=O)O7)COC6=O)C. Density: 1.48 g/cm³. Product ID: ACM38647119. Alfa Chemistry ISO 9001:2015 Certified.
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