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Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: PG490. CAS No. 38748-32-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-32735.
Triptolide
Triptolide - Product ID: NST-10-187. Category: Terpenes. Purity: 98%. Test method: HPLC. CAS No. 38748-32-2. Pack Sizes: 0,05g, 0,1g, 0,25g, 0,5g. Appearance: White powder. Molecular formula: C20H24O6. Mole weight: 360.4. Storage: +2 +8 °C.
Triptolide-d3 (major, contains d0)
Labeled Triptolite , diterpenoid triepoxide with immunosuppressant and antitumor properties. Group: Biochemicals. Alternative Names: (3bS, 4aS, 5aS, 6R, 6aR, 7aS, 7bS, 8aS, 8bS)-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Triptolide Liposome (PEGylated)
Triptolide (TP) is an epoxy diterpene lactone isolated from Tripterygium wilfordii Hook. f., which has been shown to inhibit the proliferation of hepatocellular carcinoma. This product is a pre-formulated liposome encapsulating Triptolide. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
Triptolide O-Methyl Phosphate-d3 Disodium Salt
Triptolide O-Methyl Phosphate-d3 Disodium Salt. Group: Biochemicals. Alternative Names: Minnelide-d3. Grades: Highly Purified. Pack Sizes: 500ug. Molecular Formula: C21H22D3Na2O10P, Molecular Weight: 517.39. US Biological Life Sciences.
Worldwide
Triptolide O-Methyl Phosphate Disodium Salt
Triptolide (T815600) derivative. Diterpenoid triepoxide with immunosuppressant and antitumor properties. Group: Biochemicals. Alternative Names: Minnelide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Triptolide palmitate
Triptolide palmitate is the derivative of Triptolide (HY-32735). Triptolide palmitate exhibits cytotoxicity against cancer cell MCF-7 and A549, with IC 50 of 7.5 and 6.4 μM. Triptolide palmitate exhibits a half-time T 1/2 of 50.4 min in Sprague Dawley rats. Triptolide palmitate can be utilizd as drug carrier [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2126920-51-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-158090.
Triptolide (TPL)
Triptolide, a diterpenoid triepoxyde, a purified component of a traditional Chinese medicine, inhibits transcriptional activation of NF- kB and downregulates the expression of various NF- kB-regulated genes. Displays Immunosuppressive, anti-inflammatory, anti-angiogenic and antitumor activity. A combination of TRAIL and triptolide enhance apoptosis in cholangiocarcinoma cell lines. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
5α-Hydroxytriptolide
5α-Hydroxytriptolide is obtained from Triptolide (T815600) which is Diterpenoid triepoxide with immunosuppressant and antitumor properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 583028-68-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C20H24O7, Molecular Weight: 376.4. US Biological Life Sciences.
Worldwide
O-(Methylthio)methyl Triptolide
O-(Methylthio)methyl Triptolide is a Triptolide (T815600) derivative, used in the preparation of D-ring-modified triptolide analogues. Group: Biochemicals. Alternative Names: (3bS, 4aS, 5aR, 6R, 6aS, 7aS, 7bS, 8aS, 8bS)-b, 4, 4a, 6, 6a, 7a, 7b, 8b, 9, 10-decahydro-8b-methyl-6a-(1-methylethyl)-6-[(methylthio)methoxy]-trisoxireno[4b, 5:6, 7:8a, 9]phenanthro[1, 2-c]furan-1(3H)-one; PG 691. Grades: Highly Purified. CAS No. 847440-49-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Omtriptolide
Omtriptolide (PG490-88) is a derivative proagent of triptolide purified from the Chinese herb. Uses: Scientific research. Group: Signaling pathways. CAS No. 195883-06-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-16363.
PG490-88
PG490-88 is a semisynthetic derivative of the novel compound PG490 (triptolide) purified from a Chinese herb. It has been shown to prolong acute allograft survival in multiple experimental organ transplant models. However, the effect of PG490-88 on prevention of acute and chronic renal allograft rejection has not been determined. Kidneys of ACI or F344 rats were transplanted into bilaterally nephrectomized LEW recipients as the acute or chronic allograft rejection models, respectively. Treatment of LEW recipients with PG490-88 significantly prolonged ACI kidney graft survival in a dose-dependent manner when compared with the untreated allograft controls. LEW recipients of F344 kidney grafts who received PG490-88 for 90 days with a brief course of low-dose FK506 showed normal serum creatinine levels and markedly reduced histological changes of chronic rejection at day 90 after transplantation. These results suggest that PG490-88 significantly prolongs kidney allograft survival in an acute rejection model and prevents chronic allograft rejection in rats. Synonyms: Omtriptolide; PG490 88; YM 262; YM-262; YM262; 4-{[(3bS, 4aS, 5aR, 6R, 6aS, 7aS, 7bS, 8aS, 8bS)-6a-Isopropyl-8b-methyl-1-oxo-1, 3, 3b, 4, 4a, 6, 6a, 7a, 7b, 8b, 9, 10-dodecahydrotrisoxireno[6, 7:8a, 9:4b, 5]phenanthro[1, 2-c]furan-6-yl]oxy}-4-oxobutanoic acid. Grades: ≥98%. CAS No. 195883-06-8. Molecular formula: C24H28O9. Mole weight: 460.47.
Tripterygii TOTA Glucoside
complex chemical composition containing diterpenes, triterpenes, alkaloids and the main active ingredients triptolide and tripdiolide. Product ID: 3-00269. Properties: oil soluble powder HLB 3.0 water/oil emulsifier.
Triptonide
Triptonide is a potent antitumor and antileukemic agent. It was shown to inhibit lung cancer cell tumorigenicity by selectively attenuating the Shh-Gli1 signaling pathway. Synonyms: Triptolide, 14-deoxy-14-oxo; (-)-triptonide. Grades: >98%. CAS No. 38647-11-9. Molecular formula: C20H22O6. Mole weight: 358.39.
Triptonide
Triptonide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TRIPTONIDE;TRIPTONIDE(PRIMARY STANDARD);(3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-6a-Isopropyl-8b-methyl-3b,4,4a,7a,7b,8b,9,10-octahydrotrisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione;14-Deoxy-14-oxotriptolide;Triptolide,14-deoxy-14-oxo;NSC 165677;PG 492. Appearance: White-beige powder. CAS No. 38647-11-9. Molecular formula: C20H22O6. Mole weight: 358.39. Purity: 0.98. IUPACName: Triptonide. Canonical SMILES: CC(C)C12C(O1)C3C4(O3)C5(CCC6=C(C5CC7C4(C2=O)O7)COC6=O)C. Density: 1.48 g/cm³. Product ID: ACM38647119. Alfa Chemistry ISO 9001:2015 Certified.
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