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Trovafloxacin Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive , Gram-negative and anaerobic organisms. Trovafloxacin blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC 50 of 4 μM for PANX1 inward current. Trovafloxacin does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 147059-72-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0170. MedChemExpress MCE
Trovafloxacin Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TROVAFLOXACIN;1,8-Naphthyridine-3-carboxylic acid, 7-(1.alpha.,5.alpha.,6.alpha.)-6-amino-3-azabicyclo3.1.0hex-3-yl-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-;(1α,5α,6α)-7-(6-Amino-3-azabi-cyclo[3.1.0]hex-3-y1)-1-(2,4-difluomphenyl)-6-fluom-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid;CP-99219;Trovan:CP-99219-27;7-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-keto-1,8-naphthyridine-3-carboxylic acid;7-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;7-[(1R,5S)-6-azanyl-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid. Product Category: Inhibitors. CAS No. 147059-72-1. Molecular formula: C20H15F3N4O3. Mole weight: 416.35. Product ID: ACM Alfa Chemistry.
Trovafloxacin mesylate Trovafloxacin mesylate is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive , Gram-negative and anaerobic organisms. Trovafloxacin mesylate blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin mesylate is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC 50 of 4 μM for PANX1 inward current. Trovafloxacin mesylate does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin mesylate leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 147059-75-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103399. MedChemExpress MCE
Trovafloxacin mesylate Trovafloxacin mesylate is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin mesylate blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin mesylate is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin mesylate does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin mesylate leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-[(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Methanesulfonate; CP 99219; CP 99219-27; Trovafloxacin Methanesulfonate; Trovafloxacin Monomethanesulfonate; Trovan. Product Category: Inhibitors. Appearance: White Solid. CAS No. 147059-75-4. Molecular formula: C20H15F3N4O3. Mole weight: 512.46. Purity: >99 %. IUPACName: 7-[(1S,5R)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid; methanesulfonic acid. Canonical SMILES: CS(=O)(=O)O.C1C2C(C2N)CN1C3=C(C=C4C(=O)C(=CN(C4=N3)C5=C(C=C(C=C5)F)F)C(=O)O)F. Density: g/cm³. Product ID: ACM147059754. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Trovafloxacin mesylate Trovafloxacin mesylate is a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. It does not inhibit connexin 43 gap junction or PANX2. It leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1. It is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. It is also an inhibitor of DNA topoisomerase and gyrase. Uses: Fluorinated quinolone antibacterial. trovafloxacin mesylate blocks the activity of dna gyrase and topoisomerase iv, enzymes essential in the repliction, transcription, and repair of bacterial dna. Synonyms: 7-[(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Methanesulfonate; CP 99219; CP 99219-27; Trovafloxacin Methanesulfonate; Trovafloxacin Monomethanesulfonate; Trovan; 1,8-Naphthyridine-3-carboxylic acid, 7-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, methanesulfonate (1:1). Grades: ≥95%. CAS No. 147059-75-4. Molecular formula: C21H19F3N4O6S. Mole weight: 512.46. BOC Sciences 11
Trovafloxacin Mesylate >98% (HPLC). Group: Fluorescence/luminescence spectroscopychiral molecules. Alternative Names: Trovafloxacin monomethanesulfonate, 1,8-Naphthyridine-3-carboxylic acid, 7-[(1?,5?,6?)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, methanesulfonate (1:1), 1,8-Naphthyridine-3-carboxylic acid, 7-(6-amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, (1alpha,5alpha,6alpha)-, monomethanesulfonate (9CI), CP 99219, Trovan, Trovafloxacin methanesulfonate, 3-Azabicyclo[3.1.0]hexane, 1,8-naphthyridine-3-carboxylic acid deriv., CP 99219-27, Trovafloxacin mesylate,1,8-Naphthyridine-3-carboxylic acid, 7-[(1alpha,5alpha,6alpha)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, methanesulfonate (1:1). Alfa Chemistry Analytical Products
Trovafloxacin Mesylate Fluorinated quinolone antibacterial. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA. Group: Biochemicals. Alternative Names: 7-[(1α, 5α, 6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2, 4-difluorophenyl)-6-fluoro-1, 4-dihydro-4-oxo-1, 8-naphthyridine-3-carboxylic Acid Methanesulfonate; CP 99219; CP 99219-27; Trovafloxacin Methanesulfonate; Trovafloxacin Monomethanesulfonate; Trovan. Grades: Highly Purified. CAS No. 147059-75-4. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 3
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Alatrofloxacin Mesylate The parental prodrug of Trovafloxacin, on phagocytic, anti-inflammatory and immunomodulation events of human THP-1 monocytes. Group: Biochemicals. Alternative Names: L-Alanyl-N-[(1α, 5α, 6α)-3-[6-carboxy-8-(2, 4-difluorophenyl)-3-fluoro-5, 8-dihydro-5-oxo-1, 8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-L-alaninamide Methanesulfonate; L-Alanyl-N-[(1α, 5α, 6α)-3-[6-carboxy-8-(2, 4-difluorophenyl)-3-fluoro-5, 8-dihydro-5-oxo-1, 8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-L-alaninamide Mesylate. Grades: Highly Purified. CAS No. 146961-77-5. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 1
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Felodipine USP intermediate for Imidacloprid, Indobufen, Nitroguanidine, Nalorphine, Tazarotene, Trovafloxacin. Grades: USP. CAS No. 72509-76-3. Product ID: 8-01845. Molecular formula: C18H19Cl2NO4. Mole weight: 384.15. CarboMer Inc
N-(1α , 5α , 6α )-3-Α zabicyclo[3.1.0]hex-6-yl-carbamic Acid 1,1-Dimethylethyl Ester An intermediate of Trovafloxacin and analogs. Group: Biochemicals. Alternative Names: (1α, 5α, 6α)-3-Azabicyclo[3.1.0]hex-6-yl-. Grades: Highly Purified. CAS No. 134575-17-0. Pack Sizes: 25mg. US Biological Life Sciences. USBiological 2
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