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TTA-P2 TTA-P2 is a selective T-type calcium channel blocker. It blocks T-type currents with an IC50 of 100 nM and stabilized channel in the inactive state in rats DRGs. TTA-P2 potentially acts as an antinociceptive and an antiinflammatory agent. Synonyms: TTA-P2; TTA P2; TTAP2; (S)-3,5-Dichloro-N-((1-((2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl)-4-fluoropiperidin-4-yl)methyl)benzamide; CHEMBL488817; 3,5-dichloro-N-[[4-fluoro-1-[[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]methyl]-4-piperidinyl]methyl]Benzamide; 3,5-Dichloro-N-[(1-{[(4S)-2,2-dimethyloxan-4-yl]methyl}-4-fluoropiperidin-4-yl)methyl]benzamide. CAS No. 1072018-68-8. Molecular formula: C21H29Cl2FN2O2. Mole weight: 431.373. BOC Sciences 10
TTA-P2 TTA-P2 (T-Type calcium channel inhibitor) is a potent inhibitor of T-Type calcium channel. TTA-P2 penetrates well the CNS and blocks the native T-type currents in deep cerebellar nuclear neurons, the window current is completely abolished both for wild-type and mutant Cav3.1 channels. TTA-P2 has the potential for the research of neurology disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: T-Type calcium channel inhibitor. CAS No. 1072018-68-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-10035. MedChemExpress MCE

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