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Tubastatin A is a potent and selective HDAC6 inhibitor with an IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A also inhibits HDAC10 and metallo-?-lactamase domain-containing protein 2 (MBLAC2). Uses: Scientific research. Group: Signaling pathways. CAS No. 1252003-15-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13271A.
Tubastatin A Hydrochloride. Group: Biochemicals. Alternative Names: N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide Hydrochloride. Grades: Highly Purified. CAS No. 1310693-92-5. Pack Sizes: 10mg, 50mg, 100mg. Molecular Formula: C20H22ClN3O2, Molecular Weight: 371.86. US Biological Life Sciences.
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Tubastatin A Hydrochloride
Tubastatin A Hydrochloride (Tubastatin A HCl) is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A Hydrochloride also inhibits HDAC10 and metallo-?-lactamase domain-containing protein 2 (MBLAC2). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tubastatin A HCl; TSA HCl. CAS No. 1310693-92-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13271.
Tubastatin A trifluoroacetate
Tubastatin A trifluoroacetate. Group: Biochemicals. Alternative Names: N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide 2,2,2-trifluoroacetate. Grades: Highly Purified. CAS No. 1239262-52-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C22H22F3N3O4. US Biological Life Sciences.
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HDAC Inhibitor XXIII, Tubastatin A
The HDAC Inhibitor XXIII, Tubastatin A controls the biological activity of HDAC. This small molecule/inhibitor is primarily used for Cell Structure applications. Group: Fluorescence/luminescence spectroscopy.
HDAC Inhibitor XXIII, Tubastatin A (N-Hydroxy-4-(2-methyl-1,2,3,4-tetrahydro-pyrido[4,3-b]indol-5-ylmethyl)benzamide, HCl)
A cell-permeable carbazolohydroxamate compound that acts as a highly potent, reversible and active-site zinc-binding HDAC6 inhibitor with excellent selectivity among other HDAC isozymes (IC50=0.015, 0.854, 16.4uM for HDAC6, HDAC8 and HDAC1, respectively) with no activity towards HDAC2, 3, 4, 7, 9, 10 and 11 (IC50>30uM). Shown to induce a-tubulin hyperacetylation at 2.5uM, and offer complete neuroprotection in primary cortical rat neuronal cells against homocysteic acid (HCA)-induced oxidative stress at 10uM with no noticeable neurotoxicity. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
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