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A pyridoxal-phosphate protein. The bacterial enzyme also acts on 3-hydroxytyrosine and, more slowly, on 3-hydroxyphenylalanine. Group: Enzymes. Synonyms: L-tyrosine decarboxylase; L-(-)-tyrosine apodecarboxylase; L-tyrosine carboxy-lyase. Enzyme Commission Number: EC 4.1.1.25. CAS No. 9002-9-9. L-Tyrosine Decarboxylase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4770; tyrosine decarboxylase; EC 4.1.1.25; 9002-09-9; L-tyrosine decarboxylase; L-(-)-tyrosine apodecarboxylase; L-tyrosine carboxy-lyase. Cat No: EXWM-4770.
Tyrosine decarboxylase, Microorganism
Tyrosine decarboxylase, Microorganism (TDC) widely exists in plants, insects and different microorganisms, and is often used in biochemical research. Tyrosine decarboxylase is a pyridoxal 5'-phosphate (PLP)-dependent decarboxylase that catalyzes the removal of carboxyl groups from tyrosine to produce tyramine and carbon dioxide [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TDC; TyrDC. CAS No. 9002-9-9. Pack Sizes: 25 U. Product ID: HY-P2825.
In enzymology, a tyrosine decarboxylase (EC 4.1.1.25) is an enzyme that catalyzes the chemical reaction:L-tyrosine<-> tyramine + CO2. Hence, this enzyme has one substrate, L-tyrosine, and two products, tyramine and carbon dioxide. This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. This enzyme participates in tyrosine metabolism and alkaloid biosynthesis. It employs one cofactor, pyridoxal phosphate. Applications: L-tyrosine decarboxylase from strept oc occus faecalis has been used in a study to isolate and identify the carbonyl-active site of diamine oxidase by gas chromatographic mass spectrometry. l-tyrosine decarboxylase from strept oc occus faecalis has also been used in a study to investigate the adsorption of strept oc occus faecalis on diatomite carriers for use in biotransformations. Group: Enzymes. Synonyms: tyrosine decarboxylase; EC 4.1.1.25; L-tyrosine decarboxylase; L-(-)-tyrosine apodecarboxylase; L-tyrosine carboxy-lyase; 9002-09-9. Enzyme Commission Number: EC 4.1.1.25. CAS No. 9002-9-9. L-Tyrosine Decarboxylase. Activity: > 0.1 unit/mg solid. Storage: -20°C. Source: Streptococcus faecalis. tyrosine decarboxylase; EC 4.1.1.25; L-tyrosine decarboxylase; L-(-)-tyrosine apodecarboxylase; L-tyrosine carboxy-lyase; 9002-09-9. Cat No: NATE-0421.
In enzymology, a tyrosine decarboxylase (EC 4.1.1.25) is an enzyme that catalyzes the chemical reaction:L-tyrosine<-> tyramine + CO2. Hence, this enzyme has one substrate, L-tyrosine, and two products, tyramine and carbon dioxide. This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. This enzyme participates in tyrosine metabolism and alkaloid biosynthesis. It employs one cofactor, pyridoxal phosphate. Applications: L-tyrosine decarboxylase apoenzyme from strept oc occus faecalis has been used in a study to purify and characterize tyrosine decarboxylase and aromatic-l-amino-acid decarboxylase. l-tyrosine decarboxylase apoenzyme from strept oc occus faecalis has also been used in a study to investigate the stereospecificity of sodium borohydride reduction of tyrosine decarboxylase. Group: Enzymes. Synonyms: tyrosine decarboxylase; EC 4.1.1.25; L-tyrosine decarb. Enzyme Commission Number: EC 4.1.1.25. CAS No. 9002-9-9. L-Tyrosine Decarboxylase. Activity: <0.005 unit/mg solid (without pyridoxal 5-phosphate),> 0.05 unit/mg solid (with excess pyridoxal 5-phosphate). Storage: -20°C. Source: Streptococcus faecalis. tyrosine decarboxylase; EC 4.1.1.25; L-tyrosine decarboxylase; L-(-)-tyrosine apodecarboxylase; L-tyrosine carboxy-lyase; 9002-09-9. Cat No: NATE-0420.
3-O-Methyldopa monohydrate
3-O-Methyldopa monohydrate (3-Methoxy-L-tyrosine monohydrate) is a significant metabolite of L-DOPA produced through the action of catechol O-methyltransferase (COMT). Unlike its precursor, 3-O-Methyldopa does not serve as a substrate or inhibitor of L-amino acid decarboxylase activity. Additionally, the inhibition of COMT can amplify the anti-Parkinson effects of L-DOPA. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3-Methoxy-L-tyrosine monohydrate; 3-O-Methyl-L-DOPA monohydrate. CAS No. 200630-46-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W012264.
3-O-Methyl-L-DOPA-d3 Methyl Ester
Protected labeled 3-O-Methyl-L-DOPA. 3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-Methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA. Group: Biochemicals. Alternative Names: 3-Methoxy-d3-L-tyrosine Methyl Ester. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
3-O-Methyl-L-DOPA-d3 Monohydrate
Labeled 3-O-Methyl-L-DOPA. 3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-Methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA. Group: Biochemicals. Alternative Names: 3-(Methoxy-d3)-L-tyrosine Monohydrate; 3-(Methoxy-d3)-4-hydroxyphenylalanine Monohydrate; 3-(Methoxy-d3)-DOPA Monohydrate; 3-(Methoxy-d3)-L-tyrosine Monohydrate; 3-O-(Methyl-d3)dopa Monohydrate; L-3-(Methoxy-d3)-4-hydroxy-phenylalanine Monohydrate; L-3-O-(Methyl-d3)-DOPA Monohydrate; L-4-Hydroxy-3-(methoxy-d3)phenylalanine Monohydrate. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
3-O-Methyl-L-DOPA Methyl Ester
Protected 3-O-Methyl-L-DOPA. 3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-Methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA. Group: Biochemicals. Alternative Names: 3-Methoxy-L-tyrosine Methyl Ester. Grades: Highly Purified. CAS No. 78148-37-5. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
3-O-Methyl-L-DOPA Monohydrate
3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-Methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA. Group: Biochemicals. Alternative Names: 3-Methoxy-L-tyrosine Monohydrate; 3-Methoxy-4-hydroxyphenylalanine Monohydrate; 3-Methoxy-DOPA Monohydrate; 3-Methoxy-L-tyrosine Monohydrate; 3-O-Methyldopa Monohydrate; L-3-Methoxy-4-hydroxyphenylalanine Monohydrate; L-3-O-Methyl-DOPA Monohydrate; L-4-Hydroxy-3-methoxyphenylalanine Monohydrate. Grades: Highly Purified. CAS No. 200630-46-2. Pack Sizes: 10mg, 25mg, 50mg. US Biological Life Sciences.
Worldwide
aromatic-L-amino-acid decarboxylase
A pyridoxal-phosphate protein. The enzyme also acts on some other aromatic L-amino acids, including L-tryptophan, L-tyrosine and L-phenylalanine. Group: Enzymes. Synonyms: DOPA decarboxylase; tryptophan decarboxylase; hydroxytryptophan decarboxylase; L-DOPA decarboxylase; aromatic amino acid decarboxylase; 5-hydroxytryptophan decarboxylase; aromatic-L-amino-acid carboxy-lyase (tryptamine-forming). Enzyme Commission Number: EC 4.1.1.28. CAS No. 9042-64-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4771; aromatic-L-amino-acid decarboxylase; EC 4.1.1.28; 9042-64-2; DOPA decarboxylase; tryptophan decarboxylase; hydroxytryptophan decarboxylase; L-DOPA decarboxylase; aromatic amino acid decarboxylase; 5-hydroxytryptophan decarboxylase; aromatic-L-amino-acid carboxy-lyase (tryptamine-forming). Cat No: EXWM-4771.
An Inhibitor of ornithine decarboxylase and protein tyrosine kinase. Group: Biochemicals. Alternative Names: Phenethyl Dimethyl Caffeate. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
Carbidopa
Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM. Uses: Antiparkinson agents. Synonyms: α-Methyldopahydrazine; (S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid; N-amino-alpha-methyl-3-hydroxy-L-tyrosine; (S)-α-Hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic acid; (-)-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinnamic acid; (S)-(-)-Carbidopa; (αS)-α-Hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic Acid; (S)-Carbidopa; 1-α-(3,4-Dihydroxybenzyl)-α-hydrazinopropionic Acid; HMD; Hydrazino-α-methyldopa; Lodosin; Lodosyn; MK 486; N-Aminomethyldopa. Grades: >98%. CAS No. 28860-95-9. Molecular formula: C10H14N2O4. Mole weight: 226.23.
Carbidopa Hydrate
Carbidopa Hydrate is a hydrate form of Carbidopa. Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM. It inhibits the conversion of levodopa to dopamine. Uses: Antiparkinson agents. Synonyms: α-Methyldopahydrazine monohydrate; (S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid monohydrate; N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate; (S)-α-Hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic acid monohydrate; (-)-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinnamic acid monohydrate; Lodosin monohydrate; Lodosyn monohydrate; MK 486 monohydrate; N-Aminomethyldopa monohydrate; (S)-(-)-Carbidopa monohydrate. Grades: ≥95%. CAS No. 38821-49-7. Molecular formula: C10H14N2O4.H2O. Mole weight: 244.25.
D-Dopa
D-Dopa. Uses: Designed for use in research and industrial production. Additional or Alternative Names: D-3-(3,4-Dihydroxyphenyl)alanine;D-Tyrosine,3-hydroxy-;H-D-TYR(3-HYDROXY)-OH;H-D-PHE(3,4-DI-HYDROXY)-OH;D-3-HYDROXYTYROSINE;D-BETA-(3,4-DIHYDROXYPHENYL)ALANINE;D-3,4-DIHYDROXYPHENYLALANINE;D-DOPA. Appearance: powder. CAS No. 5796-17-8. Molecular formula: C9H11NO4. Mole weight: 197.19. Purity: 95%+. IUPACName: (2R)-2-amino-3-(3,4-dihydroxyphenyl)propanoicacid. Canonical SMILES: C1=CC(=C(C=C1CC(C(=O)O)N)O)O. Density: 1.468 g/cm³. ECNumber: 227-343-0. Product ID: ACM5796178. Alfa Chemistry ISO 9001:2015 Certified. Categories: D-dopachrome decarboxylase.
gentisate decarboxylase
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. This enzyme participates in tyrosine metabolism. Group: Enzymes. Synonyms: 2,5-dihydroxybenzoate decarboxylase; gentisate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.62. CAS No. 37290-54-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4809; gentisate decarboxylase; EC 4.1.1.62; 37290-54-3; 2,5-dihydroxybenzoate decarboxylase; gentisate carboxy-lyase. Cat No: EXWM-4809.
Methyldopa
Methyldopa (Aldomet) is a DOPA decarboxylase competitive inhibitor with an ED50 of 21.8 mg/kg. Uses: Adrenergic alpha-agonists; antihypertensive agents; sympatholytics. Synonyms: L-Tyrosine Sesquihydrate;L-Tyrosine;alpha-methyl-L-dopa;α-methyl-L-dopa;L-Tyrosine, 3-hydroxy-α-methyl-. Grades: >98%. CAS No. 555-30-6. Molecular formula: C10H13NO4. Mole weight: 211.21.
MK-351 hydrochloride
MK-351 hydrochloride is an alpha-adrenergic agonist selective for α2-adrenergic receptors. It is a psychoactive drug used as a sympatholytic or antihypertensive. It plays a role in treating hypertension and gestational hypertension. It has a dual mechanism of action. It is a competitive inhibitor of the enzyme DOPA decarboxylase, which converts L-DOPA into dopamine. It is converted to α-methylnorepinephrine by dopamine beta-hydroxylase. Uses: Mk-351 hydrochloride is a psychoactive drug used as a sympatholytic or antihypertensive. it plays a role in treating hypertension and gestational hypertension. Synonyms: MK-351 hydrochloride; MK 351 hydrochloride; MK351 hydrochloride; Alpha-Methyldopa hydrochloride;L-(-)-A-Methyldopa hydrochloride;Alpha-Methyldopa HCl;(2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid;3-Hydroxy-alpha-methyl-L-tyrosine hydrochloride;L-Tyrosine, 3-hydroxy-alpha-methyl-, hydrochloride;Methyldopa hydrochloride. Grades: >98 %. CAS No. 884-39-9. Molecular formula: C10H14ClNO4. Mole weight: 247.68.
N-Acetyl-L-tyrosine
N-Acetyl-L-tyrosine originates from tyrosine through an AA acetylase, is associated with aromatic L-amino acid decarboxylase deficiency and tyrosinemia I. Uses: Scientific research. Group: Natural products. CAS No. 537-55-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W012382.
phenylalanine decarboxylase
A pyridoxal-phosphate protein. Also acts on tyrosine and other aromatic amino acids. Group: Enzymes. Synonyms: L-phenylalanine decarboxylase; aromatic L-amino acid decarboxylase; L-phenylalanine carboxy-lyase. Enzyme Commission Number: EC 4.1.1.53. CAS No. 9075-72-3. L-Phenylalanine decarboxylase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4799; phenylalanine decarboxylase; EC 4.1.1.53; 9075-72-3; L-phenylalanine decarboxylase; aromatic L-amino acid decarboxylase; L-phenylalanine carboxy-lyase. Cat No: EXWM-4799.
Staurosporin
Staurosporine is an alkaloid isolated from the culture broth of Streptomyces staurospores and is a super-potent, cell permeable PKC inhibitor (IC50=0.7); at higher concentrations Staurosporine inhibits other protein kinases: CDK2/cyclin A (IC50=7uM) and CDK4/cyclin D (IC50=3-10uM). At a concentration of 50-100nM it is a functional neurotrophins agonist promoting neurite outgrowth in neuroblastoma, pheochromocytoma and brain primary neuronal cultures. Staurosporine inhibits a variety of kinases including PKA, PKG, MLCK, CaMK, tyrosine kinases, and phosphorylase kinase. This compound displays selectivity toward the PKC isoforms, inhibiting PKCα, PKC β, PKCγ, PKCδ, and PKCε, but not PKC?, and induces PKC translocation. Staurosporine also inhibits topoisomerase II directly by interaction with the ATP binding site, augments PMA-induced ornithine decarboxylase, and activates a bcl-2-regulated apoptosis pathway. Source:Streptomyces staurosporeus. Group: Biochemicals. Alternative Names: Antibiotic AM2282; Antibiotic 230; CCRIS 3272. Grades: Highly Purified. CAS No. 62996-74-1. Pack Sizes: 100ug, 1mg, 5mg, 10mg. Molecular Formula: C28H26N4O3, Molecular Weight: 466.53. US Biological Life Sciences.
Worldwide
L-dopachrome isomerase
A zinc enzyme. Stereospecific for L-dopachrome. Dopachrome methyl ester is a substrate, but dopaminochrome (2,3-dihydroindole-5,6-quinone) is not (see also EC 4.1.1.84, D-dopachrome decarboxylase). Group: Enzymes. Synonyms: dopachrome tautomerase; tyrosinase-related protein 2; TRP-1; TRP2; TRP-2; tyrosinase-related protein-2; dopachrome Δ7,Δ2-isomerase; dopachrome Δ-isomerase; dopachrome conversion factor; dopachrome isomerase; dopachrome oxidoreductase; dopachrome-rearranging enzyme; DCF; DCT; dopachrome keto-enol isomerase; L-dopachrome-methyl ester tautomerase. Enzyme Commission Number: EC 5.3.3.12. CAS No. 130122-81-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5492; L-dopachrome isomerase; EC 5.3.3.12; 130122-81-5; dopachrome tautomerase; tyrosinase-related protein 2; TRP-1; TRP2; TRP-2; tyrosinase-related protein-2; dopachrome Δ7,Δ2-isomerase; dopachrome Δ-isomerase; dopachrome conversion factor; dopachrome isomerase; dopachrome oxidoreductase; dopachrome-rearranging enzyme; DCF; DCT; dopachrome keto-enol isomerase; L-dopachrome-methyl ester tautomerase. Cat No: EXWM-5492.
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