Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| U0126 | U0126 is a MAPK inhibitor with antitumor activity. It inhibits MEK1 and MEK2 with IC50 values of 72 nM and 58 nM, respectively. U0126 inhibits tumorigenicity of liver cancer stem cells. Uses: Enzyme inhibitors. Synonyms: U-0126; U 0126; 1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene. Grades: >98%. CAS No. 109511-58-2. Molecular formula: C18H16N6S2. Mole weight: 380.49. |  |
| U0126 | U0126 is a potent, non-ATP competitive and selective MEK1 and MEK2 inhibitor, with IC 50 s of 72 nM and 58 nM, respectively. U0126 is an autophagy and mitophagy inhibitor [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 109511-58-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12031A. |  |
| U0126 - CAS 109511-58-2 | U0126, CAS 109511-58-2, is a potent and specific inhibitor of MEK1 (IC?? = 72 nM) and MEK2 (IC?? = 58 nM). The inhibition is noncompetitive with respect to both ATP and ERK. Group: Fluorescence/luminescence spectroscopy. |  |
| U0126-EtOH | U0126-EtOH Inhibitor. Uses: Scientific use. Product Category: T6223. CAS No. 1173097-76-1. |  |
| U0126-EtOH | U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD98059. Synonyms: U0126-EtOH; U0126EtOH; U0126 EtOH, U0126, U-0126, U 0126. Grades: >98%. CAS No. 1173097-76-1. Molecular formula: C18H16N6S2.C2H6O. Mole weight: 426.56. | |
| U0126 monoethanolate | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| InSolution U0126 - CAS 109511-58-2 | A potent and specific inhibitor of MEK1 and MEK2. Group: Fluorescence/luminescence spectroscopy. | |
| PD184161 | PD184161 is an orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner more effectively than PD098059 or U0126. PD184161 inhibited cell proliferation and induced apoptosis at concentrations of > or = 1.0 microM in a time- and concentration-dependent manner. PD184161 has antitumor effects in HCC in vitro and in vivo that appear to correlate with suppression of MEK activity. PD184161 is unable to suppress MEK activity in HCC xenografts in the long term. Synonyms: PD 184161; PD-184161; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide. CAS No. 212631-67-9. Molecular formula: C17H13BrClF2IN2O2. Mole weight: 557.56. | |
| U0124 | U0124, an inactive U0126 analog, has no effect on c-Fos and c-Jun protein or mRNA levels. U0126 is a MEK inhibitor. U0124 does not inhibit MEK at concentrations up to 100 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 108923-79-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107621. | |
| U0124 | U0124 is an inactive analog of U0126 that can be used as a negative control. U0124 has no inhibitory effects on MEK at concentrations up to 100 μM. Synonyms: U0124; U 0124; U-0124; Bis[amino (methylthio) methylene]butanedinitrile. CAS No. 108923-79-1. Molecular formula: C8H10N4S2. Mole weight: 226.31. | |
| U0124 - CAS 1140528-25-1 | A useful negative control for MEK inhibitors U0125 and U0126. Group: Fluorescence/luminescence spectroscopy. | |
| U0124 - CAS 1140528-25-1 | A useful negative control for MEK inhibitors U0125 and U0126. Uses: For analytical and research use. Group: Fluorescence/luminescence spectroscopy. CAS No. 1140528-25-1. Pack Sizes: 1MG. Mole weight: 226.32. Catalog: AP1140528251. Assay: ?95% (HPLC). | |
Our database is helping our users find suppliers everyday.
