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UBP 296 UBP 296. Group: Biochemicals. Grades: Purified. CAS No. 745055-86-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
UBP 296 UBP 296 is a selective GLUK5 (GluR5)-subunit containing kainate receptor antagonist (apparent KD = 1.09 μM) that displays ~ 90-fold selectivity over AMPA receptors and recombinant human GluR6- and KA2-containing kainate receptors. It has no activity at NMDA or group I mGlu receptors. UBP 296 was shown to selectively block kainate receptor-mediated LTP induction in rat hippocampal mossy fibers. Synonyms: UBP 296; UBP296; UBP-296; (RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione; 2-[[3-(2-amino-2-carboxyethyl)-2,6-dioxopyrimidin-1-yl]methyl]benzoic acid. Grades: ≥98% by HPLC. CAS No. 745055-86-1. Molecular formula: C15H15N3O6. Mole weight: 333.3. BOC Sciences 9

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