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| Product | Description | |
|---|---|---|
| UBP 310 | UBP 310. Group: Biochemicals. Grades: Purified. CAS No. 902464-46-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| UBP 310 | UBP 310 is a GLUK5 kainate receptor antagonist (IC50 = 130 nM), displaying 12,700-fold selectivity for GLUK5 over GLUK6. It has no activity at mGlu group I or NMDA receptors at concentrations of up to 10 μM. UBP 310 also blocks recombinant homomeric GLUK7 receptors. Synonyms: UBP310, UBP 310, UBP-310; (S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-thiophene-3-yl-methyl)-5-methylpyrimidine-2,4-dione; 3-[[3-(2-amino-2-carboxyethyl)-5-methylidene-2,6-dioxopyrimidin-3-ium-1-yl]methyl]thiophene-2-carboxylic acid. Grades: ≥98% by HPLC. CAS No. 902464-46-4. Molecular formula: C14H15N3O6S. Mole weight: 353.35. |  |
| UBP310 (GluK1/GluK3 Antagonist, UBP310, (S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-thiophene-3-yl-methyl)-5-methylpyrimidine-2,4-dione, UBP-310, UBP 310) | A potent antagonist highly selective for GluK1 (Kb = 10nM), GluK3 (IC50 = 23nM), and GluK1/K5 (Kb = 8nM) subtype kainate receptors. Does not interact with GluK2 and GluK2/K5 receptors. Low affinity to AMPA receptors (Kd = 83uM). Does not interact with mGluR1 ornMDA receptors at concentration less than 10uM. Often used in studying neuronal excitability and synaptic plasticity. Group: Biochemicals. Grades: Highly Purified. CAS No. 902464-46-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
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