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UDP-N-acetyl-D-glucosamine, a significant molecule widely employed in the field of biomedicine, possesses multifarious applications. This pivotal entity acts as a substrate in glycosylation reactions, thereby facilitating the synthesis and alteration of glycoproteins and glycolipids. Consequently, this compound assumes an indispensable role in the management of specific ailments, including congenital disorders of glycosylation and metabolic disorders characterized by impaired glycosylation. Additionally, its utilization extends to the formulation of therapeutic interventions dedicated to rectifying glycosylation-related anomalies. Synonyms: Uridine 5-diphospho-a-D-N-acetylglucosamine disodium salt. CAS No. 528-04-1. Molecular formula: C17H27N3O17P2. Mole weight: 607.4.
UDP-N-acetyl-D-glucosamine disodium salt
UDP-N-acetyl-D-glucosamine disodium salt is a crucial biochemical used in the biomedical industry for the synthesis of glycosaminoglycans, antibiotics and antifungal compounds. It plays a vital role in studying bacterial and fungal infections, as well as assisting in the production of certain drugs targeting diseases like cancer and arthritis. Synonyms: UDP GlcNAc. CAS No. 91183-98-1. Molecular formula: C17H25N3O17P2Na2. Mole weight: 651.32.
UDP-N-acetyl-D-glucosamine disodium salt
UDP-N-acetyl-D-glucosamine disodium salt is a donor substrate for O-GlcNAc transferase (N-acetylglucosaminyltransferases). The compound is useful in the synthesis of aryl azide derivatives that can be employed in the affinity labeling of glycosyltransferase and UDP-HexNAc pyrophosphorylase. Applications: A donor substrate for o-glcnac transferase. Group: Coenzymes. Synonyms: UDP-N-acetylglucosamine, UDP-GlcNAc, UDPAG. CAS No. 91183-98-1. Mole weight: 651.32. Appearance: Crystalline powder. Form: Solid. UDP-N-acetylglucosamine; UDP-GlcNAc; UDPAG; UDP-N-acetyl-D-glucosamine disodium salt; 91183-98-1. Cat No: COEC-015.
The product of the enzyme is known as core 3, one of the eight core structures of mucin-type O-glycans. O-Linked glycans are polysaccharides or oligosaccharides that are linked to a protein via the oxygen atom in the side chain of an L-serine or L-threonine residue. Group: Enzymes. Synonyms: O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III; uridine diphosphoacetylglucosamine-mucin β(1?3)-acetylglucosaminyltransferase; mucin core 3 &be. Enzyme Commission Number: EC 2.4.1.147. CAS No. 87927-96-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2373; acetylgalactosaminyl-O-glycosyl-glycoprotein β-1,3-N-acetylglucosaminyltransferase; EC 2.4.1.147; 87927-96-6; O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III; uridine diphosphoacetylglucosamine-mucin β(1?3)-acetylglucosaminyltransferase; mucin core 3 β3-GlcNAc-transferase; Core 3β-GlcNAc-transferase; UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosaminyl-R) β-1,3-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-D-glucosamine:N-acetyl-β-D-galactosaminyl-R 3-β-N-acetyl-D-glucosaminyltransferase (incorrect). Cat No: EXWM-2373.
The enzyme is involved in O-glycosylation of several proteins, such as mucins. Group: Enzymes. Synonyms: O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; β6-N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-mucin β-(1?6)-acetylglucosaminyltransferase; core 2 acetylglucosaminyltransferase; core 6-β-GlcNAc-transferase A; UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of β-D-. Enzyme Commission Number: EC 2.4.1.102. CAS No. 95978-15-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2330; β-1,3-galactosyl-O-glycosyl-glycoprotein β-1,6-N-acetylglucosaminyltransferase; EC 2.4.1.102; 95978-15-7; O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; β6-N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-mucin β-(1?6)-acetylglucosaminyltransferase; core 2 acetylglucosaminyltransferase; core 6-β-GlcNAc-transferase A; UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of β-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R) β-1,6-N-acetyl-D-glucosaminyltransferase. Cat No: EXWM-2330.
β-1,3-N-Acetyl-Hexosaminyl-transferase from Neisseria meningitides, Recombinant
In enzymology, a β-1,3-N-Acetyl-Hexosaminyl-transferase is an enzyme that catalyzes the chemical reaction: UDP-N-acetyl-D-glucosamine + β-D-galactosyl-(1?4)-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-β-D-glucosaminyl-(1?6)-β-D-galactosyl-(1?4)-N-acetyl-D-glucosaminyl-R. Group: Enzymes. Synonyms: N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-acetyllactosaminide β1?6-acetylglucosaminyltransferase; Galβ1?4GlcNAc-R β1?6 N-acetylglucosaminyltransferase; UDP-GlcNAc:Gal-R, β-D-6-N-acetylglucosaminyltransferase; β1,3 HexNAc transferase; LgtA; EC 2.4.1.150. Enzyme Commission Number: EC 2.4.1.150. CAS No. 85638-40-0. Purity: min 95% by SDS-PAGE. β-1,3-HexNAc transferase. Source: E. coli. Species: Neisseria meningitides. N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-acetyllactosaminide β1?6-acetylglucosaminyltransferase; Galβ1?4GlcNAc-R β1?6 N-acetylglucosaminyltransferase; UDP-GlcNAc:Gal-R, β-D-6-N-acetylglucosaminyltransferase; β1,3 HexNAc transferase; LgtA; EC 2.4.1.150; β-1,3-N-Acetyl-Hexosaminyl-transferase. Cat No: NATE-1489.
Requires Mn2+. Group: Enzymes. Synonyms: uridine diphosphoacetylglucosamine-acetyllactosaminide β1?3-acetylglucosaminyltransferase; poly-N-acetyllactosamine extension enzyme; UDP-N-acetyl-D-glucosamine:β-D-galactosyl-1,4-N-acetyl-β-D-glucosaminyl-1,3-β-D-galactosyl-1,4-β-D-glucosylceramide β-1,3-acetylglucosaminyltransferase. Enzyme Commission Number: EC 2.4.1.163. CAS No. 85638-39-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2388; β-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide β-1,3-acetylglucosaminyltransferase; EC 2.4.1.163; 85638-39-7; uridine diphosphoacetylglucosamine-acetyllactosaminide β1?3-acetylglucosaminyltransferase; poly-N-acetyllactosamine extension enzyme; UDP-N-acetyl-D-glucosamine:β-D-galactosyl-1,4-N-acetyl-β-D-glucosaminyl-1,3-β-D-galactosyl-1,4-β-D-glucosylceramide β-1,3-acetylglucosaminyltransferase. Cat No: EXWM-2388.
chitin synthase
Converts UDP-N-acetyl-α-D-glucosamine into chitin and UDP. Group: Enzymes. Synonyms: chitin-UDP N-acetylglucosaminyltransferase; chitin-uridine diphosphate acetylglucosaminyltransferase; chitin synthetase; trans-N-acetylglucosaminosylase; UDP-N-acetyl-D-glucosamine:chitin 4-β-N-acetylglucosaminyl-transferase. Enzyme Commission Number: EC 2.4.1.16. CAS No. 9030-18-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2384; chitin synthase; EC 2.4.1.16; 9030-18-6; chitin-UDP N-acetylglucosaminyltransferase; chitin-uridine diphosphate acetylglucosaminyltransferase; chitin synthetase; trans-N-acetylglucosaminosylase; UDP-N-acetyl-D-glucosamine:chitin 4-β-N-acetylglucosaminyl-transferase. Cat No: EXWM-2384.
D-inositol-3-phosphate glycosyltransferase
The enzyme, which belongs to the GT-B fold superfamily, catalyses the first dedicated reaction in the biosynthesis of mycothiol. The substrate was initially believed to be inositol, but eventually shown to be D-myo-inositol 3-phosphate. A substantial conformational change occurs upon UDP binding, which generates the binding site for D-myo-inositol 3-phosphate. Group: Enzymes. Synonyms: mycothiol glycosyltransferases; MshA; UDP-N-acetyl-D-glucosamine:1D-myo-inositol 3-phosphate α-D-glycosyltransferase. Enzyme Commission Number: EC 2.4.1.250. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2480; D-inositol-3-phosphate glycosyltransferase; EC 2.4.1.250; mycothiol glycosyltransferases; MshA; UDP-N-acetyl-D-glucosamine:1D-myo-inositol 3-phosphate α-D-glycosyltransferase. Cat No: EXWM-2480.
Requires Mn2+. Group: Enzymes. Synonyms: uridine diphosphoacetylglucosamine-acetyllactosaminide β1?6-acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-N-acetyl-β-D-glucosaminyl-1,3-β-D-galactosyl-1,4-β-D-glucosylceramide β-1,6-N-acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:D-galactosyl-(1?4)-N-acetyl-β-D-glucosaminyl-(1?3)-β-D-galactosyl-(1?4)-β-D-glucosyl(1<->1)ceramide 6-β-N-acetylglucosaminyltransferase. Enzyme Commission Number: EC 2.4.1.164. CAS No. 85638-40-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2389; galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide β-1,6-N-acetylglucosaminyltransferase; EC 2.4.1.164; 85638-40-0; uridine diphosphoacetylglucosamine-acetyllactosaminide β1?6-acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-N-acetyl-β-D-glucosaminyl-1,3-β-D-galactosyl-1,4-β-D-glucosylceramide β-1,6-N-acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:D-galactosyl-(1?4)-N-acetyl-β-D-glucosaminyl-(1?3)-β-D-galactosyl-(1?4)-β-D-glucosyl(1<->1)ceramide 6-β-N-acetylglucosaminyltransferase. Cat No: EXWM-2389.
The activity of the intersecting mannose residue as acceptor is dependent on two other mannose residues attached by α-1,3 and α-1,6 links. Group: Enzymes. Synonyms: uridine diphosphoacetylglucosamine-oligosaccharide acetylglucosaminyltransferase; acetylglucosamine-oligosaccharide acetylglucosaminyltransferase; UDP-GlcNAc:oligosaccharide β-N-acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:high-mannose-oligosaccharide β-1,4-N-acetylglucosaminyltransferase. Enzyme Commission Number: EC 2.4.1.197. CAS No. 123425-54-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2424; high-mannose-oligosaccharide β-1,4-N-acetylglucosaminyltransferase; EC 2.4.1.197; 123425-54-7; uridine diphosphoacetylglucosamine-oligosaccharide acetylglucosaminyltransferase; acetylglucosamine-oligosaccharide acetylglucosaminyltransferase; UDP-GlcNAc:oligosaccharide β-N-acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:high-mannose-oligosaccharide β-1,4-N-acetylglucosaminyltransferase. Cat No: EXWM-2424.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. Group: Enzymes. Synonyms: LA2 synthase; β1?3-N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-lactosylceramide β-acetylglucosaminyltransferase; lactosylceramide β-acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-β-D-glucosylceramide β-1,3-acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:β-D-galactosyl-(1?4)-β-D-glucosyl(1<->1)ceramide 3-β-N-acetylglucosaminyltransferase. Enzyme Commission Number: EC 2.4.1.206. CAS No. 83682-80-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2433; lactosylceramide 1,3-N-acetyl-β-D-glucosaminyltransferase; EC 2.4.1.206; 83682-80-8; LA2 synthase; β1?3-N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-lactosylceramide β-acetylglucosaminyltransferase; lactosylceramide β-acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-β-D-glucosylceramide β-1,3-acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:β-D-galactosyl-(1?4)-β-D-glucosyl(1<->1)ceramide 3-β-N-acetylglucosaminyltransferase. Cat No: EXWM-2433.
Transfers N-acetylglucosaminyl residues to a D-galactose residue in the partially completed lipopolysaccharide core [cf. EC 2.4.1.44 (lipopolysaccharide 3-α-galactosyltransferase), EC 2.4.1.58 (lipopolysaccharide glucosyltransferase I) and EC 2.4.1.73 (lipopolysaccharide glucosyltransferase II)]. Group: Enzymes. Synonyms: UDP-N-acetylglucosamine-lipopolysaccharide N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-lipopolysaccharide acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:lipopolysaccharide N-acetyl-D-glucosaminyltransferase. Enzyme Commission Number: EC 2.4.1.56. CAS No. 37277-64-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2601; lipopolysaccharide N-acetylglucosaminyltransferase; EC 2.4.1.56; 37277-64-8; UDP-N-acetylglucosamine-lipopolysaccharide N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-lipopolysaccharide acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:lipopolysaccharide N-acetyl-D-glucosaminyltransferase. Cat No: EXWM-2601.
mannotetraose 2-α-N-acetylglucosaminyltransferase
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. Group: Enzymes. Synonyms: α-N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine mannoside α1?2-αcetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:mannotetraose α-N-acetyl-D-glucosaminyltransferase. Enzyme Commission Number: EC 2.4.1.138. CAS No. 81032-47-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2363; mannotetraose 2-α-N-acetylglucosaminyltransferase; EC 2.4.1.138; 81032-47-5; α-N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine mannoside α1?2-αcetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:mannotetraose α-N-acetyl-D-glucosaminyltransferase. Cat No: EXWM-2363.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. Group: Enzymes. Synonyms: UDP-GlcNAc:dolichyl-pyrophosphoryl-GlcNAc GlcNAc transferase; uridine diphosphoacetylglucosamine-dolichylacetylglucosamine pyrophosphate acetylglucosaminyltransferase; N, N'-diacetyl chitobiosyl pyrophosphoryl dolichol synthase; UDP-N-acetyl-D-glucosamine:N-acetyl-D-glucosaminyl-diphosphodolichol N-acetyl-D-glucosaminyltransferase. Enzyme Commission Number: EC 2.4.1.141. CAS No. 75536-54-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2367; N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase; EC 2.4.1.141; 75536-54-8; UDP-GlcNAc:dolichyl-pyrophosphoryl-GlcNAc GlcNAc transferase; uridine diphosphoacetylglucosamine-dolichylacetylglucosamine pyrophosphate acetylglucosaminyltransferase; N, N'-diacetyl chitobiosyl pyrophosphoryl dolichol synthase; UDP-N-acetyl-D-glucosamine:N-acetyl-D-glucosaminyl-diphosphodolichol N-acetyl-D-glucosaminyltransferase. Cat No: EXWM-2367.
Acts on β-galactosyl-1,4-N-acetylglucosaminyl termini on asialo-α1-acid glycoprotein and other glycoproteins and oligosaccharides. Group: Enzymes. Synonyms: uridine diphosphoacetylglucosamine-acetyllactosaminide β1?3-acetylglucosaminyltransferase; poly-N-acetyllactosamine extension enzyme; Galβ1?4GlcNAc-R β1?3 N-acetylglucosaminyltransferase; UDP-GlcNAc:GalR, β-D-3-N-acetylglucosaminyltransferase; N-acetyllactosamine β(1-3)N-acetylglucosaminyltransfer. Enzyme Commission Number: EC 2.4.1.149. CAS No. 85638-39-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2375; N-acetyllactosaminide β-1,3-N-acetylglucosaminyltransferase; EC 2.4.1.149; 85638-39-7; uridine diphosphoacetylglucosamine-acetyllactosaminide β1?3-acetylglucosaminyltransferase; poly-N-acetyllactosamine extension enzyme; Galβ1?4GlcNAc-R β1?3 N-acetylglucosaminyltransferase; UDP-GlcNAc:GalR, β-D-3-N-acetylglucosaminyltransferase; N-acetyllactosamine β(1-3)N-acetylglucosaminyltransferase; UDP-GlcNAc:Galβ1?4GlcNAcβ-Rβ1?3-N-acetylglucosaminyltransferase; GnTE; UDP-N-acetyl-D-glucosamine:β-D-galactosyl-1,4-N-acetyl-D-glucosamine β-1,3-acetyl-D-glucosaminyltransferase. Cat No: EXWM-2375.
Acts on β-galactosyl-1,4-N-acetylglucosaminyl termini on asialo-α1-acid glycoprotein. Group: Enzymes. Synonyms: N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-acetyllactosaminide β1?6-acetylglucosaminyltransferase; Galβ1?4GlcNAc-R β1?6 N-acetylglucosaminyltransferase; UDP-GlcNAc:Gal-R, β-D-6-N-acetylglucosaminyltransferasel UDP-N-acetyl-D-glucosamine:β-D-galactosyl-1,4-N-acetyl-D-glucosaminide β-1,6-N-acetyl-D-glucosaminyltransferase. Enzyme Commission Number: EC 2.4.1.150. CAS No. 85638-40-0. β-1,3-HexNAc transferase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2377; N-acetyllactosaminide β-1,6-N-acetylglucosaminyl-transferase; EC 2.4.1.150; 85638-40-0; N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-acetyllactosaminide β1?6-acetylglucosaminyltransferase; Galβ1?4GlcNAc-R β1?6 N-acetylglucosaminyltransferase; UDP-GlcNAc:Gal-R, β-D-6-N-acetylglucosaminyltransferasel UDP-N-acetyl-D-glucosamine:β-D-galactosyl-1,4-N-acetyl-D-glucosaminide β-1,6-N-acetyl-D-glucosaminyltransferase. Cat No: EXWM-2377.
Involved in the first step of glycosylphosphatidylinositol (GPI) anchor formation in all eukaryotes. In mammalian cells, the enzyme is composed of at least five subunits (PIG-A, PIG-H, PIG-C, GPI1 and PIG-P). PIG-A subunit is the catalytic subunit. In some species, the long-chain acyl groups of the phosphatidyl group are partly replaced by long-chain alkyl or alk-1-enyl groups. Group: Enzymes. Synonyms: UDP-N-acetyl-D-glucosamine:phosphatidylinositol N-acetyl-D-glucosaminyltransferase; uridine diphosphoacetylglucosamine α1,6-acetyl-D-glucosaminyltransferase. Enzyme Commission Number: EC 2.4.1.198. CAS No. 144388-35-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2425; phosphatidylinositol N-acetylglucosaminyltransferase; EC 2.4.1.198; 144388-35-2; UDP-N-acetyl-D-glucosamine:phosphatidylinositol N-acetyl-D-glucosaminyltransferase; uridine diphosphoacetylglucosamine α1,6-acetyl-D-glucosaminyltransferase. Cat No: EXWM-2425.
Involved in the synthesis of teichoic acids. Group: Enzymes. Synonyms: UDP acetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:poly(ribitol-phosphate) N-acetyl-D-glucosaminyltransferase. Enzyme Commission Number: EC 2.4.1.70. CAS No. 37277-71-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2614; poly(ribitol-phosphate) N-acetylglucosaminyltransferase; EC 2.4.1.70; 37277-71-7; UDP acetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:poly(ribitol-phosphate) N-acetyl-D-glucosaminyltransferase. Cat No: EXWM-2614.
Skp1 is a cytoplasmic and nuclear protein required for the ubiquitination of cell cycle regulatory proteins and transcriptional factors. In Dictyostelium Skp1 is modified by the linear pentasaccharide Galα1-6Galα1-L-Fucα1-2Galβ1-3GlcNAc, which is attached to a hydroxyproline residue at position 143. This enzyme catalyses the first step in the building up of the pentasaccharide by attaching an N-acetylglucosaminyl group to the hydroxyproline residue. It requires dithiothreitol and a divalent cation for activity. Group: Enzymes. Synonyms: Skp1-HyPro GlcNAc-transferase; UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase; UDP-GlcNAc:Skp1-hydroxyproline GlcNAc. Enzyme Commission Number: EC 2.4.1.229. CAS No. 256531-81-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2458; [Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase; EC 2.4.1.229; 256531-81-4; Skp1-HyPro GlcNAc-transferase; UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase; UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase; UDP-GlcNAc:hydroxyproline polypeptide GlcNAc-transferase; UDP-N-acetyl-D-glucosamine:[Skp1-protein]-hydroxyproline N-acetyl-D-glucosaminyl-transferase. Cat No: EXWM-2458.
N-Acetylglucosamine end-groups in glycoproteins can also act as acceptors. Group: Enzymes. Synonyms: uridine diphosphogalactose-uridine diphosphoacetylglucosamine galactose-1-phosphotransferase; galactose-1-phosphotransferase; galactosyl phosphotransferase; UDP-galactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase. Enzyme Commission Number: EC 2.7.8.18. CAS No. 84932-43-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3317; UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase; EC 2.7.8.18; 84932-43-4; uridine diphosphogalactose-uridine diphosphoacetylglucosamine galactose-1-phosphotransferase; galactose-1-phosphotransferase; galactosyl phosphotransferase; UDP-galactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase. Cat No: EXWM-3317.
UDP-GlcNAc 4-epimerase from Plesiomonas shigelloides O17, Recombinant
In enzymology, an UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) is an enzyme that catalyzes the chemical reaction: UDP-N-acetyl-D-glucosamine ? UDP-N-acetyl-D-galactosamine. Hence, this enzyme has one substrate, UDP-N-acetyl-D-glucosamine, and one product, UDP-N-acetyl-D-galactosamine. This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. Group: Enzymes. Synonyms: UDP-N-acetyl-D-glucosamine 4-epimerase; UDP acetylglucosamine epimerase; uridine diphosphoacetylglucosamine epimerase; uridine diphosphate N-acetylglucosamine-4-epimerase; uridine 5'-diphospho-N-acetylglucosamine-4-epimerase. Enzyme Commission Number: EC 5.1.3.7. CAS No. 9024-16-2. Purity: min 95% by SDS-PAGE. UDP-GlcNAc 4-Epimerase. Mole weight: 38 kDa. Source: E. coli. Species: Plesiomonas shigelloides O17. UDP-N-acetyl-D-glucosamine 4-epimerase; UDP acetylglucosamine epimerase; uridine diphosphoacetylglucosamine epimerase; uridine diphosphate N-acetylglucosamine-4-epimerase; uridine 5'-diphospho-N-acetylglucosamine-4-epimerase; UDP-GlcNAc 4-Epimerase. Cat No: NATE-1497.
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase. This enzyme participates in amino sugars metabolism and glycan biosynthesis. Group: Enzymes. Synonyms: MurA transferase; UDP-N-acetylglucosamine 1-carboxyvinyl-transferase; UDP-N-acetylglucosamine enoylpyruvyltransferase; enoylpyruvate transferase; phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltran. Enzyme Commission Number: EC 2.5.1.7. CAS No. 9023-27-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2807; UDP-N-acetylglucosamine 1-carboxyvinyltransferase; EC 2.5.1.7; 9023-27-2; MurA transferase; UDP-N-acetylglucosamine 1-carboxyvinyl-transferase; UDP-N-acetylglucosamine enoylpyruvyltransferase; enoylpyruvate transferase; phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase; phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase; phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase; phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase; phosphopyruvate-uridine diphosphoace
This bacterial enzyme catalyses the reversible interconversion of UDP-GlcNAc and UDP-ManNAc. The latter is used in a variety of bacterial polysaccharide biosyntheses.cf. EC 3.2.1.183, UDP-N-acetylglucosamine 2-epimerase (hydrolysing). Group: Enzymes. Synonyms: UDP-N-acetylglucosamine 2'-epimerase (ambiguous); uridine diphosphoacetylglucosamine 2'-epimerase (ambiguous); uridine diphospho-N-acetylglucosamine 2'-epimerase (ambiguous); uridine diphosphate-N-acetylglucosamine-2'-epimerase (ambiguous); rffE (gene name); mnaA (gene name); UDP-N-acetyl-D-glucosamine 2-epimerase. Enzyme Commission Number: EC 5.1.3.14. CAS No. 9037-71-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5399; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing); EC 5.1.3.14; 9037-71-2; UDP-N-acetylglucosamine 2'-epimerase (ambiguous); uridine diphosphoacetylglucosamine 2'-epimerase (ambiguous); uridine diphospho-N-acetylglucosamine 2'-epimerase (ambiguous); uridine diphosphate-N-acetylglucosamine-2'-epimerase (ambiguous); rffE (gene name); mnaA (gene name); UDP-N-acetyl-D-glucosamine 2-epimerase. Cat No: EXWM-5399.
UDP-N-acetylglucosamine 4-epimerase
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. This enzyme participates in aminosugars metabolism. Group: Enzymes. Synonyms: UDP acetylglucosamine epimerase; uridine diphosphoacetylglucosamine epimerase; uridine diphosphate N-acetylglucosamine-4-epimerase; uridine 5'-diphospho-N-acetylglucosamine-4-epimerase; UDP-N-acetyl-D-glucosamine 4-epimerase. Enzyme Commission Number: EC 5.1.3.7. CAS No. 9024-16-2. UDP-GlcNAc 4-Epimerase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5430; UDP-N-acetylglucosamine 4-epimerase; EC 5.1.3.7; 9024-16-2; UDP acetylglucosamine epimerase; uridine diphosphoacetylglucosamine epimerase; uridine diphosphate N-acetylglucosamine-4-epimerase; uridine 5'-diphospho-N-acetylglucosamine-4-epimerase; UDP-N-acetyl-D-glucosamine 4-epimerase. Cat No: EXWM-5430.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups transferases for other substituted phosphate groups. This enzyme participates in the biosynthesis of n-glycan and glycan structures. Group: Enzymes. Synonyms: UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase; UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase; UDP-. Enzyme Commission Number: EC 2.7.8.15. CAS No. 70431-08-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3315; UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase; EC 2.7.8.15; 70431-08-2; UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase; UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase; UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase; uridine diphosphoacetylglucosamine-dolichyl phosphate acetylglucosamine-1-phosphotransferase; chitobiosylpyrophosphoryldolichol synthase; dolichol phosphate N-acetylglucosamine-1-phosphotransferase; UDP-acetylglucosamine-dolichol phosphate acetylglucosamine phosphotransferase; UDP-acetylglucosamine-dolichol phosphate acetylglucosamine-1-phosphotransferase. Cat No: EXWM-3315.
The enzyme, characterized from the methanogenic archaeon Methanococcus voltae, initiates N-linked glycosylation in that organism. The enzyme differs from the eukaryotic enzyme, which leaves one additional phosphate group on the dolichyl product (cf. EC 2.7.8.15, UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase). Group: Enzymes. Synonyms: aglK (gene name); dolichyl-phosphate α-N-acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:dolichyl-phosphate α-N-acetyl-D-glucosaminyltransferase. Enzyme Commission Number: EC 2.4.1.153. CAS No. 63363-73-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2379; UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminyltransferase; EC 2.4.1.153; 63363-73-5; aglK (gene name); dolichyl-phosphate α-N-acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:dolichyl-phosphate α-N-acetyl-D-glucosaminyltransferase. Cat No: EXWM-2379.
UDP-N-acetylglucosamine kinase
Toxic component of a toxin-antitoxin (TA) module. The phosphorylation of UDP-N-acetyl-D-glucosamine results in the inhibition of EC 2.5.1.7, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, the first committed step in cell wall synthesis, which is then blocked. The activity of this enzyme is inhibited when the enzyme binds to the cognate ε antitoxin. Group: Enzymes. Synonyms: UNAG kinase; ζ toxin; toxin PezT; ATP:UDP-N-acetyl-D-glucosamine 3'-phosphotransferase. Enzyme Commission Number: EC 2.7.1.176. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3007; UDP-N-acetylglucosamine kinase; EC 2.7.1.176; UNAG kinase; ζ toxin; toxin PezT; ATP:UDP-N-acetyl-D-glucosamine 3'-phosphotransferase. Cat No: EXWM-3007.
This enzyme catalyses the synthesis of N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol, an essential lipid intermediate for the biosynthesis of various bacterial cell envelope components. The enzyme also initiates the biosynthesis of enterobacterial common antigen and O-antigen lipopolysaccharide in certain Escherichia coli strains, including K-12 and of teichoic acid in certain Gram-positive bacteria. Group: Enzymes. Synonyms: UDP-N-acetylglucosamine:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; WecA; WecA transferase; UDP-GIcNAc:undecaprenyl phosphate N-acetylglucosaminyl 1-P transfe. Enzyme Commission Number: EC 2.7.8.33. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3332; UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase; EC 2.7.8.33; UDP-N-acetylglucosamine:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; WecA; WecA transferase; UDP-GIcNAc:undecaprenyl phosphate N-acetylglucosaminyl 1-P transferase; GlcNAc-P-P-Und synthase; GPT (ambiguous); TagO; UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; UDP-N-acetyl-D-glucosamine:ditrans,octacis-undecaprenyl phosphate N-acetylglucosaminephosphotransferase. Cat No: EXWM-3332.
The enzyme also works when the lysine residue is replaced by meso-2,6-diaminoheptanedioate (meso-2,6-diaminopimelate, A2pm) combined with adjacent residues through its L-centre, as it is in Gram-negative and some Gram-positive organisms. The undecaprenol involved is ditrans,octacis-undecaprenol (for definitions, click here). Group: Enzymes. Synonyms: MurG transferase; UDP-N-acetyl-D-glucosamine:N-acetyl-α-D-muramyl(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol β-1,4-N-acetylglucosaminlytransferase. Enzyme Commission Number: EC 2.4.1.227. CAS No. 60976-26-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2456; undecaprenyldiphospho-muramoylpentapeptide β-N-acetylglucosaminyltransferase; EC 2.4.1.227; 60976-26-3; MurG transferase; UDP-N-acetyl-D-glucosamine:N-acetyl-α-D-muramyl(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol β-1,4-N-acetylglucosaminlytransferase. Cat No: EXWM-2456.
xylogalacturonan β-1,3-xylosyltransferase
Involved in plant cell wall synthesis. The enzyme from Arabidopsis thaliana also transfers D-xylose from UDP-D-xylose onto oligogalacturonide acceptors. The enzyme did not show significant activity with UDP-glucose, UDP-galactose, or UDP-N-acetyl-D-glucosamine as sugar donors. Group: Enzymes. Synonyms: xylogalacturonan xylosyltransferase; XGA xylosyltransferase. Enzyme Commission Number: EC 2.4.2.41. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2670; xylogalacturonan β-1,3-xylosyltransferase; EC 2.4.2.41; xylogalacturonan xylosyltransferase; XGA xylosyltransferase. Cat No: EXWM-2670.
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