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UK 370106 UK 370106. Group: Biochemicals. Grades: Purified. CAS No. 230961-21-4. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 5
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UK 370106 UK 370106 is a highly selective MMP-3 and MMP-12 inhibitor (IC50 = 0.023, 0.042, 1.75, 2.3, 5.8, 30.4, 34.2 and 66.9 μM at MMP 3, 12, 8, 13, 7, 9, 2 and 14, respectively). UK 370106 inhibits fibronectin cleavage (IC50 = 320 nM), and substantially inhibits MMP-3 in an ex vivo model of chronic dermal ulcers. Uses: The treatment of chronic dermal ulcers. Synonyms: UK 370106; UK370106; UK-370106; (βR)-β-[[[(1S)-1-[[[(1S)-2-Methoxy-1-phenylethyl]amino]carbonyl]-2,2-dimethylpropyl]amino]carbonyl]-2-methyl-[1,1'-biphenyl]-4-hexanoic acid; (3R)-3-[[(2S)-1-[[(1S)-2-methoxy-1-phenylethyl]amino]-3,3-dimethyl-1-oxobutan-2-yl]carbamoyl]-6-(3-methyl-4-phenylphenyl)hexanoic acid. Grades: ≥95% by HPLC. CAS No. 230961-21-4. Molecular formula: C35H44N2O5. Mole weight: 572.73. BOC Sciences 10
[2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene]chloro(p-cymene)ruthenium Chloride [2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene]chloro(p-cymene)ruthenium Chloride is used as a catalyst in the asymmetric synthesis of UK 370106 (U700620); an MMP-3 inhibitor. It is also highly effective in the hydrogenation of 2-(6'-methoxy-2'-naphthyl)propenoic acid and β-ketoesters. Group: Biochemicals. Grades: Highly Purified. CAS No. 130004-33-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C54H46Cl2P2Ru. US Biological Life Sciences. USBiological 10
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