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| Product | Description | |
|---|---|---|
| UK-371804 | UK-371804 is a novel and selective inhibitors of urokinase plasminogen activator (uPA). UK-371804 exhibits excellent enzyme potency (Ki 10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin). Synonyms: 2- ( (4-chloro-1- ( (diaminomethylene) amino) isoquinoline) -7-sulfonamido) -2-methylpropanoic acid; UK-371804; UK371804; UK 371804; UK-371,804; UK 371,804; UK371,804. Grades: >98%. CAS No. 256477-09-5. Molecular formula: C14H16ClN5O4S. Mole weight: 385.82. |  |
| UK-371804 HCl | UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor. Study in vitro showed that it inhibited exogenous uPA in human chronic wound fluid (IC50=0.89 mM); In a porcine acute excisional wound model, it penetrated into pig wounds and suppressed exogenous uPA activity. UK-371804 is promisingly to be used for the treatment of chronic dermal ulcers. Synonyms: UK-371804 HCl; UK 371804 HCl; UK371804 HCl; SCHEMBL6437767; 2-[[4-chloro-1-(diaminomethylideneamino)isoquinolin-7-yl]sulfonylamino]-2-methylpropanoic acid hydrochloride. Grades: 99.56 %. CAS No. 256476-36-5. Molecular formula: C14H16ClN5O4S.HCl. Mole weight: 422.29. | |
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