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| Product | Description | |
|---|---|---|
| Ulixertinib | Ulixertinib, also known as VRT752271, is an inhibitor of ERK protein kinase. Synonyms: (S)-4-(5-chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide; BVD-523; BVD 523; BVD523; VRT752271; VRT752271; VRT 752271; Ulixertinib. Grades: 98%. CAS No. 869886-67-9. Molecular formula: C21H22Cl2N4O2. Mole weight: 433.333. |  |
| Ulixertinib | Ulixertinib (BVD-523; VRT752271) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC 50 of <0.3 nM against ERK2. Ulixertinib (BVD-523; VRT752271) inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BVD-523; VRT752271. CAS No. 869886-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15816. |  |
| Ulixertinib HCl | Ulixertinib, also known as BVD-523 and VRT752271 is a potent and reversible ERK1/ERK2 inhibitor with IC50 of <0.3 nM for ERK2. Upon oral administration, BVD-523 inhibits both ERK 1 and 2, thereby preventing the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. Synonyms: (S)-4-(5-chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide hydrochloride.; BVD-523; BVD 523; BVD523; VRT752271; VRT752271; VRT 752271; Ulixertinib hydrochloride. CAS No. 1956366-10-1. Molecular formula: C21H23Cl3N4O2. Mole weight: 469.79. | |
| Ulixertinib hydrochloride | Ulixertinib hydrochloride (BVD-523 hydrochloride) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC 50 of <0.3 nM against ERK2. Ulixertinib hydrochloride inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BVD-523 hydrochloride; VRT752271 hydrochloride. CAS No. 1956366-10-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15816A. | |
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