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| Product | Description | |
|---|---|---|
| UNC0321 | UNC0321 is a potent and selective histone methyltransferase G9a inhibitor with a Ki of 63 pM and with assay-dependent IC50 values of 6-9 nM. UNC0321 also inhibits GLP with assay-dependent IC50 values of 15-23 nM. UNC0321 has anti-apoptotic activity and has potential application in diabetic vascular complications[1][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1238673-32-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10930. |  |
| UNC0321 (TFA Salt) | UNC0321 (trifluoroacetate salt) is a selective histone lysine methyltransferase (HMTase) inhibitor for G9a and GLP (also known as EHMT1), with IC50 of 6nM and 15nM, respectively. It is more than 40,000-fold more selective for G9a and GLP vs. SET7/9, SET8, PRMT3, or JMJD2E. Group: Biochemicals. Alternative Names: 4-Quinazolinamine, 7-[2-[2- (dimethylamino) ethoxy]ethoxy]-2- (hexahydro-4-methyl-1H-1, 4-diazepin-1-yl) -6-methoxy-N- (1-methyl-4-piperidinyl) -, trifluoroacetate. Grades: Highly Purified. CAS No. 1238673-32-9 (free base). Pack Sizes: 50mg. US Biological Life Sciences. |  Worldwide |
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