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| Product | Description | |
|---|---|---|
| UNC0379 | UNC0379 is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 ( KMT5A ) with an IC 50 of 7.3 μM, K D value of 18.3 μM. UNC0379 can be used in the research of inflammation and cancers, such as pulmonary fibrosis, ovarian cancer, neuroblastoma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1620401-82-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12335. |  |
| UNC0379 | UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8. UNC0379 is active in multiple biochemical assays. Its affinity to SETD8 was confirmed by ITC (isothermal titration calorimetry) and SPR (surface plasmon resonance) studies. Importantly, UNC0379 is selective for SETD8 over 15 other methyltransferases. Synonyms: UNC0379, UNC-0379, UNC 0379. Grades: 0.98. CAS No. 1620401-82-2. Molecular formula: C23H35N5O2. Mole weight: 413.566. |  |
| UNC0379 trifluoroacetate | UNC0379 trifluoroacetate is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8 with IC50 of 7.3±1.0 uM; selective over 15 other methyltransferases. Synonyms: UNC-0379 trifluoroacetate; UNC 0379 trifluoroacetate; UNC0379 trifluoroacetate. Grades: >98%. CAS No. 1620401-83-3. Molecular formula: C25H36F3N5O4. Mole weight: 527.58. | |
| UNC0379 trifluoroacetate salt | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
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