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UNC6934 UNC6934, a chemical probe targeting the PWWP domain, alters NSD2 nucleolar localization. Uses: Scientific research. Group: Signaling pathways. CAS No. 2561494-77-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145103. MedChemExpress MCE
UNC6934 UNC6934 is a novel potent antagonist of NSD2-PWWP1 with a Kd (SPR) of 80 ± 18 nM, being selective for NSD2-PWWP1 over 14 other PWWP domains including NSD3-PWWP1, the closest on the phylogenetic tree, disrupting the NSD2-PWWP1 interaction with H3K36me2 nucleosomes in U2OS cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: UNC6934; UNC-6934; UNC 6934. Product Category: Antagonists. Appearance: Solid powder. CAS No. 2561494-77-5. Molecular formula: C24H21N5O4. Mole weight: 443.46. Purity: >98%. IUPACName: N-Cyclopropyl-3-oxo-N-(4-(pyrimidin-4-ylcarbamoyl)benzyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carboxamide. Canonical SMILES: O=C(C1=CC=C(N2)C(OCC2=O)=C1)N(C3CC3)CC4=CC=C(C(NC5=NC=NC=C5)=O)C=C4. Product ID: ACM2561494775. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.

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