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uracil-DNA glycosylase Uracil-DNA glycosylases are widespread enzymes that are found in all living organisms. EC 3.2.2.27 and double-stranded uracil-DNA glycosylase (EC 3.2.2.28) form a central part of the DNA-repair machinery since they initiate the DNA base-excision repair pathway by hydrolysing the N-glycosidic bond between uracil and the deoxyribose sugar thereby catalysing the removal of mis-incorporated uracil from DNA. Group: Enzymes. Synonyms: UdgB (ambiguous); uracil-DNA N-glycosylase; UDG (ambiguous); uracil DNA glycohydrolase. Enzyme Commission Number: EC 3.2.2.27. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3981; uracil-DNA glycosylase; EC 3.2.2.27; UdgB (ambiguous); uracil-DNA N-glycosylase; UDG (ambiguous); uracil DNA glycohydrolase. Cat No: EXWM-3981. Creative Enzymes
double-stranded uracil-DNA glycosylase No activity on DNA containing a T/G mispair or single-stranded DNA containing either a site-specific uracil or 3,N4-ethenocytosine residue, significant role for double-stranded uracil-DNA glycosylase in mutation avoidance in non-dividing E. coli. Uracil-DNA glycosylases are widespread enzymes that are found in all living organisms. Uracil-DNA glycosylase (EC 3.2.2.27) and EC 3.2.2.28 form a central part of the DNA-repair machinery since they initiate the DNA base-excision repair pathway by hydrolysing the N-glycosidic bond between uracil and the deoxyribose sugar thereby catalysing the removal of mis-incorporated uracil from DNA. Group: Enzymes. Synonyms: Mug; double-strand uracil-DNA glycosylase; Dug; dsUDG; double-stranded DNA specific UDG; dsDNA specific UDG; UdgB (ambiguous); G:T/U mismatch-specific DNA glycosylase; UDG (ambiguous). Enzyme Commission Number: EC 3.2.2.28. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3982; double-stranded uracil-DNA glycosylase; EC 3.2.2.28; Mug; double-strand uracil-DNA glycosylase; Dug; dsUDG; double-stranded DNA specific UDG; dsDNA specific UDG; UdgB (ambiguous); G:T/U mismatch-specific DNA glycosylase; UDG (ambiguous). Cat No: EXWM-3982. Creative Enzymes
1-[(5E)-5,6-Dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]uracil 1-[(5E)-5,6-Dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]uracil, an extraordinary biomedicine, manifests its potential as a breakthrough antiviral agent. By adeptly targeting the viral uracil-DNA glycosylase enzyme, it inhibits viral replication and hinders viral DNA synthesis. Its molecular architecture, distinctive and resolute, engenders unrivaled selectivity and efficacy across diverse viral strains. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[(5E)-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]-; 1-[(2R,3R,4R,5R)-5-[(E)-2-diethoxyphosphorylethenyl]-4-hydroxy-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 2095417-05-1. Molecular formula: C15H23N2O8P. Mole weight: 390.33. BOC Sciences 3

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