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DBCO-Val-Cit-PAB-MMAE DBCO-Val-Cit-PAB-MMAE is a drug-linker conjugate, which can be used for the synthesis of ADC molecules. MMAE (HY-15162) is a tubulin inhibitor, which can be used as an ADC toxin. DBCO-Val-Cit-PAB is the linker with the electrophilic group [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2768446-73-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-W591408. MedChemExpress MCE
mDPR-Val-Cit-PAB-MMAE mDPR-Val-Cit-PAB-MMAE consists the ADCs linker (mDPR-Val-Cit-PAB) and potent tubulin inhibitor (MMAE), mDPR-Val-Cit-PAB-MMAE is an antibody drug conjugate. Synonyms: N-[(2S)-3-Amino-2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoyl]-L-valyl-N-{4-[(5S,8S,11S,12R)-11-[(2S)-2-butanyl]-12-(2-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2 ;-methyl-3-oxopropyl]-1-pyrrolidinyl}-2-oxoethyl)-5,8-diisopropyl-4,10-dimethyl-3,6,9-trioxo-2,13-dioxa-4,7,10-triazatetradec-1-yl]phenyl}-N5-carbamoyl-L-ornithinamide; L-Ornithinamide, N-[(2S)-3-amino-2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[(5S,8S,11S,12R)-12-[2-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenyl ethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-oxoethyl]-4,10-dimethyl-5,8-bis(1-methylethyl)-11-[(1S)-1-methylpropyl]-3,6,9-trioxo-2,13-dioxa-4,7,10-triazatetradec-1-yl]phenyl]-. Grades: ≥95%. CAS No. 1491152-26-1. Molecular formula: C65H100N12O15. Mole weight: 1289.561. BOC Sciences 5
DBCO-PEG4-VC-PAB-MMAE SPAAC & SPANC Click Reaction. Group: Dbco. Alternative Names: DBCO-PEG4-Val-Cit-PAB-MMAE. CAS No. 2129164-91-4. Molecular formula: C88H128N12O19. Mole weight: 1658.1. Purity: 0.98. IUPACName: [4- [ [ (2S) -2- [ [ (2S) -2- [3- [2- [2- [2- [2- [ [4- (2-Azatricyclo [10. 4. 0. 04, 9] hexadeca-1 (16) , 4, 6, 8, 12, 14-hexaen-10-yn-2-yl) -4-oxobutanoyl] amino] ethoxy] ethoxy] ethoxy] ethoxy] propanoylamino] -3-methylbutanoyl] amino] -5- (carbamoylamino) pentanoyl] amino] phenyl] methyl N-[(2S)-1-[[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-N-methylcarbamate. Canonical SMILES: CCC (C)C (C (CC (=O)N1CCCC1C (C (C)C (=O)NC (C)C (C2=CC=CC=C2)O)OC)OC)N (C)C (=O)C (C (C)C)NC (=O)C (C (C)C)N (C)C (=O)OCC3=CC=C (C=C3)NC (=O)C (CCCNC (=O)N)NC (=O)C (C (C)C)NC (=O)CCOCCOCCOCCOCCNC (=O)CCC (=O)N4CC5=CC=CC=C5C#CC6=CC=CC=C64. Catalog: CCR2129164914. Alfa Chemistry. 2
Telisotuzumab vedotin Telisotuzumab vedotin (ABBV-399) is an antibody-drug conjugate ( ADCs ) targeting c-Met. Telisotuzumab vedotin consists of Monomethyl Auristatin E (MMAE), Telisotuzumab antibody and a cleavable mc-val-cit-PABC type linker. Telisotuzumab vedotin can be used to study non-small cell lung cancer expressing c-Met protein [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABBV-399. CAS No. 1714088-51-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-141601. MedChemExpress MCE

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