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| Product | Description | |
|---|---|---|
| Valbenazine | Valbenazine is a potent and highly selective vesicular monoamine transporter 2(VMAT2) inhibitor. It is a prodrug of the (+)-α isomer of tetrabenazine for tardive syndrome therapy. It is effective in regulating the levels of dopamine release during nerve communication, while at the same time having minimal impact on the other monoamines. It significantly improved tardive dyskinesia and was well tolerated in patients. It is an experimental drug being investigated for use in the treatment of tardive dyskinesia and Tourette syndrome. It was developed by Neurocrine Biosciences. Uses: Valbenazine is an experimental drug being investigated for use in the treatment of tardive dyskinesia and tourette syndrome. Synonyms: Ingrezza; L-Valine, (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo(a)quinolizin-2-yl ester; (S)-2-amino-3-methyl-butyric acid (2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl ester; Tetrabenazine Related Impurity 28 (2R, 3R, 11bR, L-Val); [(2R,3R,11bR)-9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl] (2S)-2-amino-3-methylbutanoate; NBI-98854; NBI98854; MT-5199; MT5199; NBI 98854; MT 5199. Grades: >98%. CAS No. 1025504-45-3. Molecular formula: C24H38N2O4. Mole weight: 418.57. |  |
| Valbenazine | Valbenazine (NBI-98854) is a vesicular monoamine transporter 2 ( VMAT2 ) inhibitor with the K i of 110-190 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NBI-98854. CAS No. 1025504-45-3. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16771. |  |
| 2-Hydroxy Valbenazine | 2-Hydroxy Valbenazine is an impurity of Valbenazine (V087000), a highly selective vesicular monoamine transporter 2 inhibitor. It is used in the treatment of tardive dykinesia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H36N2O5, Molecular Weight: 420.54. US Biological Life Sciences. |  Worldwide |
| 2-Hydroxy Valbenazine-d8 | Isotope labelled 2-Hydroxy Valbenazine is an impurity of Valbenazine (V087000), a highly selective vesicular monoamine transporter 2 inhibitor. It is used in the treatment of tardive dykinesia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H28D8N2O5, Molecular Weight: 428.59. US Biological Life Sciences. | Worldwide |
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