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Vatalanib, also called as PTK 787 or CGP 797870, is a small molecule that interacts reversibly and competitively at the ATP-binding site of the receptor tyrosine kinase domain to inhibit autophosphorylation. It targets all known VEGFR tyrosine kinases. Synonyms: N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine; PTK787; PTK 787; PTK-787; ZK 222584; ZK222584; ZK-222584; CGP 79787; CGP-797870; ZK-232934; CGP79787D; ZK 222584; CGP-7978. Grades: >98%. CAS No. 212141-54-3. Molecular formula: C20H15ClN4. Mole weight: 346.81.
Vatalanib
Vatalanib (PTK787; ZK-222584; CGP-79787) is an inhibitor of VEGFR2/KDR with IC 50 of 37 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTK787; ZK-222584; CGP-79787. CAS No. 212141-54-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10203.
Vatalanib-d4 Dihydrochloride
Labeled Vatalanib. Vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitor. Antineoplastic. Group: Biochemicals. Alternative Names: N-(4-Chlorophenyl-d4)-4-(4-pyridinylmethyl)-1-phthalazinamine Dihydrochloride; CGP-79787-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Vatalanib dihydrochloride
Vatalanib dihydrochloride. Group: Biochemicals. Alternative Names: N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine dihydrochloride; CGP-79787. Grades: Highly Purified. CAS No. 212141-51-0. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C20H17Cl3N4. US Biological Life Sciences.
Worldwide
Vatalanib dihydrochloride
Vatalanib dihydrochloride (PTK787 dihydrochloride) is an inhibitor of VEGFR2/KDR with IC 50 of 37 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTK787 dihydrochloride; ZK-222584 dihydrochloride; CGP-797870 dihydrochloride. CAS No. 212141-51-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12018.
Vatalanib dihydrochloride
Vatalanib (PTK787; ZK-222584; CGP-79787) is an inhibitor of VEGFR2/KDR with IC50 of 37 nM, less potent against VEGFR1/Flt-1, 18-fold against VEGFR3/Flt-4. Uses: Protein kinase inhibitors. Synonyms: PTK787; PTK 787; PTK-787; ZK 222584; ZK222584; ZK-222584; CGP 79787; CGP-797870; ZK-232934; CGP79787D; PTK787/ZK 222584; CGP-7978. nchembio778-comp1; PTK/ZK; D06285; CGP79787D; PTK787/ZK 222584. Grades: 0.98. CAS No. 212141-51-0. Molecular formula: C20H15ClN4.2HCl. Mole weight: 419.73.
Vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitor. Antineoplastic. Group: Biochemicals. Alternative Names: N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine Dihydrochloride; CGP-79787 Dihydrochloride. Grades: Highly Purified. CAS No. 212141-51-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Vatalanib succinate
Vatalanib succinate is a potent and orally bioactive VEGFR inhibitor (IC50 = 37 and 77 nM for VEGFR-2 and -1, respectively) exhibiting potential antineoplastic activity. Vatalanib binds to the protein kinase domain of VEGFR, and inhibits proliferation, migration and survival of HUVECs in vitro. Vatalanib also inhibits PDGFR-β, c-Kit and c-Fms. Synonyms: N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine succinate; CGP 79787D; PTK 787; ZK 222584; CGP79787D; PTK787; ZK222584; CGP-79787D; PTK-787; ZK-222584. Grades: ≥99% by HPLC. CAS No. 212142-18-2. Molecular formula: C20H15ClN4.C4H6O4. Mole weight: 464.9.
Angiogenesis related Compound Library
A unique collection of 1370 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS); - Targets include angiogenesis signaling, and related targets such as S1P, VEGFR, PDGF, etc. ; - Includes approved drugs targeting angiogenesis, such as Sunitinib Malate, Lenalidomide, sorafenib, Erlotinib; drugs in clinical development with the most potential targeting angiogenesis, such as Vatalanib, Orantinib, 2-Methoxyestradiol (Panzem), Celecoxib; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4800. Categories: Angiogenesis related Compounds Libraries.
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