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| Product | Description | |
|---|---|---|
| Vatalanib succinate | 1-[4-Chloroanilino]-4-[4-pyridylmethyl]phthalazine succinate. CAS No. 212142-18-2. Product ID: 8-04313. Molecular formula: C24H21ClN4O4 C20H15ClN4 C4H6O4. Mole weight: 464.9. |  |
| Vatalanib succinate | Vatalanib succinate is a potent and orally bioactive VEGFR inhibitor (IC50 = 37 and 77 nM for VEGFR-2 and -1, respectively) exhibiting potential antineoplastic activity. Vatalanib binds to the protein kinase domain of VEGFR, and inhibits proliferation, migration and survival of HUVECs in vitro. Vatalanib also inhibits PDGFR-β, c-Kit and c-Fms. Synonyms: N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine succinate; CGP 79787D; PTK 787; ZK 222584; CGP79787D; PTK787; ZK222584; CGP-79787D; PTK-787; ZK-222584. Grades: ≥99% by HPLC. CAS No. 212142-18-2. Molecular formula: C20H15ClN4.C4H6O4. Mole weight: 464.9. |  |
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