Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Verubecestat | Verubecestat, an iminothiadiazine dioxide compound, is an oral BACE1 inhibitor originated by Merck & Co. It can bind significantly to β-secretase. Verubecestat has the potent effect to treat Alzheimer's disease and is currently in Phase III clinical trials. Uses: Alzheimer's disease. Synonyms: N-[3-[(5R)-3-amino-2,5-dimethyl-1,1-dioxo-6H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoropyridine-2-carboxamide; J1I0P6WT7T; Verubecestat; UNII-J1I0P6WT7T; J1I0P6WT7T; 1286770-55-5; Verubecestat [USAN]; Verubecestat (USAN/INN); GTPL8699; CHEMBL3301601; SCHEMBL10328722; SCHEMBL17507398; BDBM143220; example 25 (US8940748); SCH-900931; D10739; US8940748, 25; 2-Pyridinecarboxamide, N-(3-((5R)-3-amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2H-1,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoro-; N-(3-((5R)-3-amino-2,5-dimethyl-1,1-dioxo-1,2,5,6-tetrahydro-1lambda6,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropyridine-2-carboxamide; N-(3-((5R)-3-amino-2,5-dimethyl-1,1-dioxo-5,6-dihydro-2H-1lambda6,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropyridine-2-carboxamide; N-[3-[(5R)-3-amino-2,5-dimethyl-1,1-dioxo-6H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoropyridine-2-carboxamide. Grades: 98%. CAS No. 1286770-55-5. Molecular formula: C17H17F2N5O3S. Mole weight: 409.41. |  |
| Verubecestat | Verubecestat (MK-8931) is an orally active, high-affinity BACE1 and BACE2 inhibitor with K i values of 2.2 nM and 0.38 nM. Verubecestat effectively reduces Aβ40 and has the potential for Alzheimer's Disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-8931. CAS No. 1286770-55-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16759. |  |
| Verubecestat TFA | Verubecestat, also known as MK-8931 or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MK-8931; MK 8931; MK8931; MK-8931-009; SCH 900931; SCH-900931; SCH900931; Verubecestat TFA. Product Category: Inhibitors. Appearance: White to off-white solid powder. CAS No. 2095432-65-6. Molecular formula: C19H18F5N5O5S. Mole weight: 523.44. Purity: >98%. IUPACName: (R)-N-(3-(3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2H-1,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropicolinamide trifluoroacetic acid. Canonical SMILES: O=C(NC1=CC=C(F)C([C@@](C2)(C)N=C(N)N(C)S2(=O)=O)=C1)C3=NC=C(F)C=C3.O=C(O)C(F)(F)F. Product ID: ACM2095432656. Alfa Chemistry ISO 9001:2015 Certified. |  |
Our database is helping our users find suppliers everyday.
