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Vinflunine is a new vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity. Synonyms: Vinflunine; 162652-95-1; Javlor; UNII-5BF646324K; 20',20'-difluoro-3',4'-dihydrovinorelbine. Grades: 0.98. CAS No. 162652-95-1. Molecular formula: C45H54F2N4O8. Mole weight: 816.944.
Vinflunine ditartrate
Vinflunine, a semisynthetic derivative of Vinorelbine, is the first fluorinated microtubule inhibitor belonging to the Vinca alkaloids family endowed with unique antitumor properties. Uses: Semisynthetic vinca alkaloid with microtubule destabilizing and antiangiogenic activity; derivative of vinorelbine. antineoplastic. Synonyms: 4'-Deoxy-20',20'-difluoro-5'-norvincaleukoblastine Ditartrate; 20',20'-Difluoro-3',4'-dihydrovinorelbine Ditartrate; BMS 710485; F 12158; Javlor. Grades: >98%. CAS No. 194468-36-5. Molecular formula: C53H66F2N4O20. Mole weight: 1117.10.
Vinflunine ditartrate
Vinflunine ditartrate is the first fluorinated microtubule inhibitor belonging to the Vinca alkaloids family. Vinflunine ditartrate has anti-angiogenic, vascular-disrupting and anti-metastatic activities. Vinflunine ditartrate can be used for the research of transitional cell carcinoma of the urothelial tract, non-small cell lung cancer, and carcinoma of the breast. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4'-Deoxy-20',20'-difluoro-5'-norvincaleukoblastine Ditartrate; 20',20'-Difluoro-3',4'-dihydrovinorelbine Ditartrate; BMS 710485; F 12158; Javlor. Product Category: Inhibitors. Appearance: White Solid. CAS No. 194468-36-5. Molecular formula: C53H66F2N4O20. Mole weight: 1117.1. Canonical SMILES: OC([C@H](O)[C@@H](O)C(O)=O)=O.OC([C@H](O)[C@@H](O)C(O)=O)=O.CC[C@@]1(C=CCN2CC3)[C@@]2([H])[C@@]3(C(C=C([C@](C4=C5C(C=CC=C6)=C6N4)(CC(C[C@@H](C(F)(F)C)C7)([H])CN7C5)C(OC)=O)C(OC)=C8)=C8N9C)[C@]9([H])[C@](C(OC)=O)(O)[C@@H]1OC(C)=O. Product ID: ACM194468365. Alfa Chemistry ISO 9001:2015 Certified.
Vinflunine Ditartrate
Vinflunine is a semisynthetic Vinca alkaloid with microtubule destabilizing and antiangiogenic activity. Vinflunine is a derivative of Vinorelbine. Vinflunine is used as an antineoplastic. Group: Biochemicals. Alternative Names: (2 β,3 β,4 β,5α,12 β,19α)-4-(Acetyloxy)-6,7-didehydro-15-[(2R,4R,6S,8S)-4-(1,1-difluoroethyl)-1,3,4,5,6,7,8,9-octahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methylaspidospermidine-3-carboxylic Acid Methyl Ester (2R,3R)-2,3-Dihydroxybutanedioate; 4'-Deoxy-20',20'-difluoro-5'-nor-vincaleukoblastine Ditartrate; 20',20'-Difluoro-3',4'-dihydrovinorelbine Ditartrate; BMS 710485; F 12158; Javlor. Grades: Highly Purified. CAS No. 194468-36-5. Pack Sizes: 5mg. US Biological Life Sciences.
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Vinflunine Liposome
Vinflunine is a novel fluorinated vinca alkaloid derivative that exerts antitumor effects by inhibiting the cell proliferation of microtubule proteins. This product is a PEGylated pre-formulated liposome with vinflunine ditartrate. It is only for research purposes. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes.
Vinflunine Tartrate
Vinflunine induces apoptosis in neuroblastoma SK-N-SH cells through a postmitotic G1 arrest and a mitochondrial pathway in a concentration-dependent manner with an IC50 with 50 nM. Grades: >98%. CAS No. 1201898-17-0. Molecular formula: C45H54F2N4O8.xC4H6O6. Mole weight: 967.02.
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