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| Product | Description | |
|---|---|---|
| Vonoprazan | Vonoprazan (TAK-438 free base), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB) , with antisecretory activity. Vonoprazan inhibits H + ,K + -ATPase activity in porcine gastric microsomes with an IC 50 of 19 nM at pH 6.5. Vonoprazan is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan can be used for eradication of Helicobacter pylori [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-438 free base. CAS No. 881681-00-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-100007. |  |
| Vonoprazan-[d3] | Vonoprazan-[d3] is a labelled Vonoprazan, a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+ ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. Synonyms: Vonoprazan-d3. Molecular formula: C17H13D3FN3O2S. Mole weight: 348.4. |  |
| Vonoprazan Fumarate | Vonoprazan Fumarate (TAK-438), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB) , with antisecretory activity. Vonoprazan Fumarate inhibits H + ,K + -ATPase activity in porcine gastric microsomes with an IC 50 of 19 nM at pH 6.5. Vonoprazan Fumarate is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-438. CAS No. 881681-01-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-15295. | |
| Vonoprazan Impurity 27 | Vonoprazan Impurity 27. Uses: For analytical and research use. Group: Impurity standards. CAS No. 122453-85-4. Molecular formula: C11H8N2. Mole weight: 168.2. Catalog: APB122453854. |  |
| Vonoprazan Impurity 34 | Vonoprazan Impurity 34. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1240948-72-4. Molecular formula: C11H6ClFN2. Mole weight: 220.63. Catalog: APB1240948724. | |
| Vonoprazan Impurity 36 | Vonoprazan Impurity 36. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1060802-18-7. Molecular formula: C5H3Cl2NO2S. Mole weight: 212.04. Catalog: APB1060802187. | |
| Vonoprazan Impurity 51 | Vonoprazan Impurity 51. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1240949-51-2. Molecular formula: C11H7FN2. Mole weight: 186.19. Catalog: APB1240949512. | |
| Vonoprazan Impurity 64 | Vonoprazan Impurity 64. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1240948-77-9. Molecular formula: C11H7FN2. Mole weight: 186.19. Catalog: APB1240948779. | |
| 2-Chloro Vonoprazan | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 2-Chloro Vonoprazan; 928325-68-2; 1-(2-Chloro-5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine; 1-[2-chloro-5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine; SCHEMBL1580961; CS-0164589; 1-(2-chloro-5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine? (Vonoprazan Impurity pound(c). Grade: 95%. CAS No. 928325-68-2. Molecular formula: C17H15ClFN3O2S. Mole weight: 379.84. | |
| 1-(2-((2,4-dimethylphenyl)sulfonyl)phenyl)piperazine | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well as a Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: Piperazine, 1-[2-[(2,4-dimethylphenyl)sulfonyl]phenyl]-; Vortioxetine Sulfone; Vonoprazan Impurity 10. CAS No. 1639263-80-1. Molecular formula: C18H22N2O2S. Mole weight: 330.44. | |
| 1-(4-((2,4-dimethylphenyl)thio)phenyl)piperazine | One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well as a Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: Vortioxetine impurity S; Piperazine, 1-[4-[(2,4-dimethylphenyl)thio]phenyl]-; Vonoprazan Impurity 08. CAS No. 1815608-51-5. Molecular formula: C18H22N2S. Mole weight: 298.45. | |
| 1-(5-(2-fluorophenyl)-1-(pyridin-2-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine fumarate | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: Vonoprazan Impurity 33. Grade: 95% HPLC. CAS No. 928615-46-7. Molecular formula: C17H16FN3O2S. Mole weight: 345.39. | |
| 1-Methyl-4-sulfopyridinium Hydroxide Inner Salt | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 1-methyl-4-sulfopyridin-1-ium hydroxide; 4416-69-7. Grade: 95%. CAS No. 4416-69-7. Molecular formula: C6H7NO3S. Mole weight: 173.19. | |
| 2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 3-(2-Fluorophenyl)-3-oxopropane-1,1-dicarbonitrile; Vonoprazan Impurity 02. CAS No. 312307-38-3. Molecular formula: C11H7FN2O. Mole weight: 202.18. | |
| 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: Vonoprazan Impurity 50. CAS No. 2169267-53-0. Molecular formula: C11H7ClFNO. Mole weight: 223.63. | |
| 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 1H-Pyrrole-3-carbonitrile, 2-chloro-5-(2-fluorophenyl)-; Vonoprazan Impurity 33; Vonoprazan Impurity 03. CAS No. 1240948-72-4. Molecular formula: C11H6ClFN2. Mole weight: 220.63. | |
| 2-chloro-5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 1H-Pyrrole-3-carboxaldehyde, 2-chloro-5-(2-fluorophenyl)-1-(3-pyridinylsulfonyl)-; Vonoprazan Impurity 41. CAS No. 928324-80-5. Molecular formula: C16H10ClFN2O3S. Mole weight: 364.78. | |
| 2'-Fluoroacetophenone | 2'-Fluoroacetophenone (Vonoprazan Impurity 31). Group: Biochemicals. Grades: Highly Purified. CAS No. 445-27-2. Pack Sizes: 500mg, 1g. Molecular Formula: C8H7FO, Molecular Weight: 138.139999999999. US Biological Life Sciences. |  Worldwide |
| 5-((2-(2-fluorophenyl)-4-((methylamino)methyl)-1H-pyrrol-1-yl)sulfonyl)-1,2,3,4-tetrahydropyridin-2-ol | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: Vonoprazan Impurity U2 Fumaric acid; TAK438 Impurity 42 Monomer; Vonoprazan N-Methyl Asparmic Acid Impurity. Grade: 98%. CAS No. 2416241-96-6. Molecular formula: C17H20FN3O3S. Mole weight: 365.42. | |
| 5-(2-Fluorophenyl)-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-carbonitrile | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Grade: 95%. CAS No. 1807642-39-2. Molecular formula: C16H10FN3O2S. Mole weight: 327.33. | |
| 5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 1H-Pyrrole-3-carboxaldehyde, 5-(2-fluorophenyl)-; Vonoprazan Impurity 01. Grade: 98%. CAS No. 881674-56-2. Molecular formula: C11H8FNO. Mole weight: 189.19. | |
| 5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 1H-Pyrrole-3-carbonitrile, 5-(2-fluorophenyl)-; Vonoprazan Impurity 04. CAS No. 1240948-77-9. Molecular formula: C11H7FN2. Mole weight: 186.18. | |
| 5-(2-fluorophenyl)-1-(pyridin-2-ylsulfonyl)-1H-pyrrole-3-carbaldehyde | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 1H-Pyrrole-3-carboxaldehyde, 5-(2-fluorophenyl)-1-(2-pyridinylsulfonyl)-; Vonoprazan Impurity 39. CAS No. 928324-73-6. Molecular formula: C16H11FN2O3S. Mole weight: 330.33. | |
| (5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 1H-Pyrrole-3-methanamine, 5-(2-fluorophenyl)-1-(3-pyridinylsulfonyl)-; 5-(2-Fluorophenyl)-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine; Vonoprazan Impurity 24. CAS No. 1807642-41-6. Molecular formula: C16H14FN3O2S. Mole weight: 331.36. | |
| (5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine fumarate | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C20H18FN3O6S. Mole weight: 447.44. | |
| 5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carboxylic acid | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: N,N-bis((5-(2-fluorophenyl)-1H-pyrrol-3-yl)methyl)pyridine-3-sulfonamide; Vonoprazan Impurity 16. CAS No. 1883595-37-6. Molecular formula: C16H11FN2O4S. Mole weight: 346.33. | |
| 5-(2-fluorophenyl)-N-methyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carboxamide | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: Vonoprazan Impurity 47. CAS No. 2054536-04-6. Molecular formula: C17H14FN3O3S. Mole weight: 359.37. | |
| 5-Chloropyridine-3-sulfonyl chloride | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 5-Chloro-3-pyridinesulfonyl chloride; Vonoprazan Impurity 36. CAS No. 1060802-18-7. Molecular formula: C5H3Cl2NO2S. Mole weight: 212.05. | |
| GenBank CX447129 (9CI) | pyridine-3-sulfonyl chloride is mainly used for preparing TAK-438 (vonoprazan fumarate), which is a novel orally active potassium-competitive acid blocker, developed as an antisecretory drug. Synonyms: 3-Pyridinesulfonyl chloride; m-Pyridinesulfonyl Chloride; chloro-3-pyridylsulfone. Grade: 95%. CAS No. 813222-82-1. Molecular formula: C5H4ClNO2S. Mole weight: 177.61. | |
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