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| Product | Description | |
|---|---|---|
| Vonoprazan Fumarate | Vonoprazan Fumarate (TAK-438), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB) , with antisecretory activity. Vonoprazan Fumarate inhibits H + ,K + -ATPase activity in porcine gastric microsomes with an IC 50 of 19 nM at pH 6.5. Vonoprazan Fumarate is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-438. CAS No. 881681-01-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-15295. |  |
| GenBank CX447129 (9CI) | pyridine-3-sulfonyl chloride is mainly used for preparing TAK-438 (vonoprazan fumarate), which is a novel orally active potassium-competitive acid blocker, developed as an antisecretory drug. Synonyms: 3-Pyridinesulfonyl chloride; m-Pyridinesulfonyl Chloride; chloro-3-pyridylsulfone. Grade: 95%. CAS No. 813222-82-1. Molecular formula: C5H4ClNO2S. Mole weight: 177.61. |  |
| 1-(5-(2-fluorophenyl)-1-(pyridin-2-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine fumarate | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: Vonoprazan Impurity 33. Grade: 95% HPLC. CAS No. 928615-46-7. Molecular formula: C17H16FN3O2S. Mole weight: 345.39. | |
| 5-((2-(2-fluorophenyl)-4-((methylamino)methyl)-1H-pyrrol-1-yl)sulfonyl)-1,2,3,4-tetrahydropyridin-2-ol | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: Vonoprazan Impurity U2 Fumaric acid; TAK438 Impurity 42 Monomer; Vonoprazan N-Methyl Asparmic Acid Impurity. Grade: 98%. CAS No. 2416241-96-6. Molecular formula: C17H20FN3O3S. Mole weight: 365.42. | |
| (5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine fumarate | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C20H18FN3O6S. Mole weight: 447.44. | |
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