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| Product | Description | |
|---|---|---|
| VU 0360172 | VU 0360172. Group: Biochemicals. Alternative Names: N-Cyclobutyl-6-[2-(3-fluorophenyl)ethynyl]-3-pyridinecarboxamide Hydrochloride. Grades: Highly Purified. CAS No. 1309976-62-2. Pack Sizes: 10mg. Molecular Formula: C18H16ClFN2O, Molecular Weight: 330.78. US Biological Life Sciences. |  Worldwide |
| VU 0360172 hydrochloride | VU 0360172 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1309976-62-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU 0360172 hydrochloride | VU 0360172 hydrochloride is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM) with potential antipsychotic-like activity. VU 0360172 has no significant activity at mGlu1, mGlu2 or mGlu4 receptors. VU 0360172 has been shown to decrease spontaneous spike and wave discharges without affecting motor behavior in a rat model of absence epilepsy. Synonyms: VU 0360172 hydrochloride; VU0360172 hydrochloride; VU-0360172 hydrochloride; N-Cyclobutyl-6-[2-(3-fluorophenyl)ethynyl]-3-pyridinecarboxamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 1309976-62-2. Molecular formula: C18H15FN2O.HCl. Mole weight: 330.78. |  |
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